Diabetic retinopathy is a heterogeneous retinal degenerative disease with the microvascular
dysfunction being recognized as a hallmark of the advanced stage. In this study, we …

Microvascular dysfunctions due to altered interactions between endothelial cells (ECs) and
pericytes are key-events in the pathogenesis of diabetic retinopathy. Extracellular vesicles …

Diabetic retinopathy (DR) has characteristics of early loss of capillary pericytes, contributing
to aberrant endothelial proliferation and angiogenesis. The function of extracellular vesicles …

Previous studies have reported that endothelial-to-mesenchymal transition (EndoMT)
contributes to pathological fibrosis in proliferative diabetic retinopathy (PDR). The …

Aims Extracellular vesicle (EV)-transferred microRNAs (miRNAs) are proved to be
potentially therapeutic candidates. Here, we attempted to unveil the role of delivery of miR …

Diabetic retinopathy (DR) is a common microvascular complication. Many studies have
focused on the role of microRNAs (miRNAs) in DR but not specifically on miR-133b-3p …

Diabetic retinopathy is a sight-threatening complication of diabetes, characterized by loss of
retinal pericytes and abnormal angiogenesis. We previously demonstrated that extracellular …

Early diagnosis and precise monitoring of the development of proliferative diabetic
retinopathy (PDR) can significantly improve therapeutic strategies and help decrease …

Aims Diabetic retinopathy (DR) is characterized by early dropout of capillary pericytes,
leading to loss of control on endothelial proliferation and, subsequently, angiogenesis. We …

Rationale: Microglia with a repertoire of functions are critical in pathological regulation of
angiogenesis in the retina. However, retinal microglia with beneficial contributions and …