Radial stem astrocytes (aka neural stem cells): identity, development, physio‐pathology, and therapeutic potential
CY Yeh, KY Wu, GJ Huang, A Verkhratsky - Acta Physiologica, 2023 - Wiley Online Library
Adult neurogenesis is a striking example of neuroplasticity, which enables adaptive network
remodelling in response to all forms of environmental stimulation in physiological and …
remodelling in response to all forms of environmental stimulation in physiological and …
Neuronal stem cells in the central nervous system and in human diseases
Q Wu, X Wang - Protein & cell, 2012 - Springer
The process of cortical expansion in the central nervous system is a key step of mammalian
brain development to ensure its physiological function. Radial glial (RG) cells are a glial cell …
brain development to ensure its physiological function. Radial glial (RG) cells are a glial cell …
Glial cells generate neurons—master control within CNS regions: developmental perspectives on neural stem cells
M Götz - The Neuroscientist, 2003 - journals.sagepub.com
A common problem in neural stem cell research is the poor generation of neuronal or
oligodendroglial descendants. The author takes a developmental perspective to propose …
oligodendroglial descendants. The author takes a developmental perspective to propose …
Novel perspectives of neural stem cell differentiation: from neurotransmitters to therapeutics
CA Trujillo, TT Schwindt, AH Martins… - Cytometry Part A …, 2009 - Wiley Online Library
In the past years, many reports have described the existence of neural progenitor and stem
cells in the adult central nervous system capable of generating new neurons, astrocytes, and …
cells in the adult central nervous system capable of generating new neurons, astrocytes, and …
Stars from the darkest night: unlocking the neurogenic potential of astrocytes in different brain regions
JP Magnusson, J Frisén - Development, 2016 - journals.biologists.com
In a few regions of the adult brain, specialized astrocytes act as neural stem cells capable of
sustaining life-long neurogenesis. In other, typically non-neurogenic regions, some …
sustaining life-long neurogenesis. In other, typically non-neurogenic regions, some …
Adult neural stem cells: born to last
AV Morales, H Mira - Frontiers in Cell and Developmental Biology, 2019 - frontiersin.org
The generation of new neurons is a lifelong process in many vertebrate species that
provides an extra level of plasticity to several brain circuits. Frequently, neurogenesis in the …
provides an extra level of plasticity to several brain circuits. Frequently, neurogenesis in the …
Adult neurogenesis from reprogrammed astrocytes
The details of adult neurogenesis, including environmental triggers, region specificity, and
species homology remain an area of intense investigation. Slowing or halting age-related …
species homology remain an area of intense investigation. Slowing or halting age-related …
An update on human astrocytes and their role in development and disease
Human astrocytes provide trophic as well as structural support to the surrounding brain cells.
Furthermore, they have been implicated in many physiological processes important for …
Furthermore, they have been implicated in many physiological processes important for …
The novel roles of glial cells revisited: the contribution of radial glia and astrocytes to neurogenesis
T Mori, A Buffo, M Götz - Current topics in developmental biology, 2005 - Elsevier
Astroglial cells are the most frequent cell type in the adult mammalian brain, and the number
and range of their diverse functions are still increasing. One of their most striking roles is …
and range of their diverse functions are still increasing. One of their most striking roles is …
Glial influences on neural stem cell development: cellular niches for adult neurogenesis
Neural stem cells continually generate new neurons in very limited regions of the adult
mammalian central nervous system. In the neurogenic regions there are unique and highly …
mammalian central nervous system. In the neurogenic regions there are unique and highly …