The clinical and diagnostic significance of anti-myosin autoantibodies in cardiac disease

U Nussinovitch, Y Shoenfeld - Clinical reviews in allergy & immunology, 2013 - Springer
Autoimmunity is influenced by genetic, immune, hormonal, and environmental factors. Viral
infections may trigger autoimmunity. It has been established that autoimmunity may be a …

Autoantibodies against cardiac myosin in patients with myocarditis and dilated cardiomyopathy

B Lauer, K Padberg, HP Schultheiss… - Zeitschrift fur …, 1995 - europepmc.org
Evidence accumulated in recent years indicates that autoimmunologic mechanisms may
play an important role in the pathogenesis of myocarditis and dilated cardiomyopathy. In …

[HTML][HTML] Autoantibodies in against human ventricular myosin in sera of patients with acute and chronic myocarditis

B Lauer, K Padberg, HP Schultheiss… - Journal of the American …, 1994 - Elsevier
Objectives. The present study investigated the presence of antimyosin autoantibodies in
sera of patients with myocarditis and in three control groups: healthy blood donors, patients …

Circulating cardiac-specific autoantibodies as markers of autoimmunity in clinical and biopsy-proven myocarditis

ALP Caforio, JH Goldman, AJ Haven… - European heart …, 1997 - academic.oup.com
Aim Myocarditis and dilated cardiomyopathy may be phases of an organ-specific
autoimmune disease of the myocardium. To provide evidence for autoimmune involvement …

Cardiac autoantibodies to myosin and other heart-specific autoantigens in myocarditis and dilated cardiomyopathy

ALP Caforio, NJ Mahon, WJ McKenna - Autoimmunity, 2001 - Taylor & Francis
Dilated cardiomyopathy (DCM) is characterized by dilation and impaired contraction of the
left ventricle or both; it is a relevant cause of heart failure and a common indication for heart …

Evidence for autoimmunity to myosin and other heart-specific autoantigens in patients with dilated cardiomyopathy and their relatives

ALP Caforioa, JH Goldman, AJ Haven, KM Baig… - International journal of …, 1996 - Elsevier
Autoimmune disease is characterised by the presence of circulating autoantibodies in the
affected patients and in a proportion of their relatives. These antibodies are generally not …

Consequences of unlocking the cardiac myosin molecule in human myocarditis and cardiomyopathies

A Mascaro-Blanco, K Alvarez, X Yu, JA Lindenfeld… - …, 2008 - Taylor & Francis
Myocarditis, often initiated by viral infection, may progress to autoimmune inflammatory heart
disease, dilated cardiomyopathy and heart failure. Although cardiac myosin is a dominant …

Cardiac myosin and autoimmune myocarditis

NR Rose, KW Beisel, A Herskowitz… - Ciba Foundation …, 2007 - Wiley Online Library
Infection with type 3 of the group B Coxsackieviruses (CB3) some‐times leads to the
development of myocarditis in humans. Circumstantial evidence in the form of heart‐reactive …

Autoimmunity to alpha myosin in a subset of patients with idiopathic dilated cardiomyopathy.

JH Goldman, PJ Keeling, RS Warraich, MK Baig… - Heart, 1995 - heart.bmj.com
OBJECTIVE--To use an enzyme linked immunoassay (ELISA) technique to assess
frequency and disease specificity of anti-alpha-myosin antibodies in patients with dilated …

Clinical significance and pathogenic role of anti-cardiac myosin autoantibody in dilated cardiomyopathy

Z Wang, Y Liao, J Dong, S Li, J Wang… - Chinese Medical …, 2003 - mednexus.org
Objective In order to explore the possible roles played by the autoimmune mechanism in the
progression of myocarditis into dilated cardiomyopathy (DCM) using an animal model, we …