The interplay of signaling pathways with miRNAs in cholangiocarcinoma pathogenicity and targeted therapy

MB Zaki, AI Abulsoud, SS Elshaer, D Fathi… - … -Research and Practice, 2023 - Elsevier
Cholangiocarcinoma (CCA), the second most frequent liver cancer after hepatocellular
carcinoma, has been rising worldwide in recent epidemiological research. This neoplasia's …

The potential role of miRNAs in the pathogenesis of gallbladder cancer-A focus on signaling pathways interplay

AS Doghish, HM Midan, AMM Elbadry… - … -Research and Practice, 2023 - Elsevier
Abstract microRNAs (also known as miRNAs or miRs) are a class of small non-coding RNAs
that play a critical role in post-transcriptional gene regulation as negative gene regulators by …

miRNAs orchestration of gallbladder cancer-Particular emphasis on diagnosis, progression and drug resistance

RK Shahin, MA Elkady, AI Abulsoud… - … -Research and Practice, 2023 - Elsevier
Gallbladder cancer (GBC) is characterized by a highly invasive nature and a poor prognosis,
with adenocarcinoma being the main histological subtype. According to statistical data …

miRNAs inspirations in hepatocellular carcinoma: detrimental and favorable aspects of key performers

HA El-Mahdy, AAM Sallam, A Ismail… - … -Research and practice, 2022 - Elsevier
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer-related deaths
worldwide. HCC initiation, progression, and therapy failure are all influenced by various …

Molecular mechanism of cholangiocarcinoma carcinogenesis

K Maemura, S Natsugoe… - Journal of Hepato‐Biliary …, 2014 - Wiley Online Library
Cholangiocarcinoma (CCA) is a highly malignant cancer of the biliary tract with a poor
prognosis, which often arises from conditions causing long‐term inflammation, injury, and …

The role of microRNA expression pattern in human intrahepatic cholangiocarcinoma

L Chen, HX Yan, W Yang, L Hu, LX Yu, Q Liu, L Li… - Journal of …, 2009 - Elsevier
BACKGROUND/AIMS: MicroRNAs are a small non-coding family of genes involved in the
regulation of gene expression in a post-transcriptional manner and contribute to cell …

[HTML][HTML] MicroRNA expression and its implications for diagnosis and therapy of gallbladder cancer

Z Li, X Yu, J Shen, PTY Law, MTV Chan, WKK Wu - Oncotarget, 2015 - ncbi.nlm.nih.gov
Gallbladder cancer is the most common biliary tract malignancy with poor prognosis.
MicroRNAs (miRNAs) are a class of small, endogenous, non-coding RNAs of 19–23 …

miRNAs role in bladder cancer pathogenesis and targeted therapy: signaling pathways interplay–a review

HA El-Mahdy, EGE Elsakka, AA El-Husseiny… - … -Research and Practice, 2023 - Elsevier
Bladder cancer (BC) is the 11th most popular cancer in females and 4th in males. A lot of
efforts have been exerted to improve BC patients' care. Besides, new approaches have …

[HTML][HTML] miRNA and lncRNA as biomarkers in cholangiocarcinoma (CCA)

B Zheng, S Jeong, Y Zhu, L Chen, Q Xia - Oncotarget, 2017 - ncbi.nlm.nih.gov
The microRNAs are a group of 20 nucleotides-long non-coding RNAs. By binding to the
3'UTR region of target mRNA, microRNAs can perform extensive actions mediating gene …

[PDF][PDF] Cholangiocarcinoma: molecular targeting strategies for chemoprevention and therapy

AE Sirica - Hepatology, 2005 - Wiley Online Library
Cholangiocarcinomas are devastating cancers that are increasing in both their worldwide
incidence and mortality rates. The challenges posed by these often lethal biliary tract …