Despite substantial evidence emphasizing the pleiotropic benefits of exercise for the
prevention and treatment of various diseases, the underlying biological mechanisms have …

Exercise has many beneficial effects that provide health and metabolic benefits. Signaling
molecules are released from organs and tissues in response to exercise stimuli and are …

The health benefits of exercise are well-recognized and are observed across multiple organ
systems. These beneficial effects enhance overall resilience, healthspan and longevity. The …

Physical inactivity is a major cause of chronic diseases. It shortens the health span by
lowering the age of the first chronic disease onset, which leads to decreased quality of life …

Regular exercise has both immediate and long-lasting benefits on cardiometabolic health,
and has been recommended as a cornerstone of treatment in the management of diabetes …

Exercise physiology has gained increasing interest due to its wide effects to promote health.
Recent years have seen a growth in this research field also due to the finding of several …

Garcıa-Hermoso and colleagues 1 recently published a systematic literature review and
meta-analysis on exercise training-induced changes in exerkine concentrations in type 2 …

Exercise confers numerous salutary effects that extend beyond individual organ systems to
provide systemic health benefits. Here, we discuss the role of exercise in cardiovascular …

Exercise activates a plethora of metabolic and signalling pathways in skeletal muscle and
other organs causing numerous systemic beneficial metabolic effects. Thus, regular exercise …

Several benefits can be acquired through physical exercise. Different classes of
biomolecules are responsible for the cross-talk between distant organs. The secretome of …