Liver cancer is the third greatest cause of cancer-related mortality, which of the major
pathological type is hepatocellular carcinoma (HCC) accounting for more than 90%. HCC is …

In hepatocellular carcinoma patients, due to the microenvironmental specificity of liver, the
tumor microenvironment exhibits high immunosuppression and drug resistance, resulting in …

Primary liver cancer (PLC), including hepatocellular carcinoma (HCC) and intrahepatic
cholangiocarcinoma (ICC), and other rare tumors, is the third leading cause of cancer …

The prevalence of liver cancer is constantly rising, with increasing incidence and mortality in
Europe and the USA in recent decades. Among the different subtypes of liver cancers …

Hepatocellular carcinoma (HCC) is one of the most malignant human cancers, with a high
mortality rate worldwide despite its early diagnosis in patients and improvement in …

Hepatocellular carcinoma (HCC) remains a serious medical therapeutic challenge as
conventional curative avenues such as surgery and chemotherapy only benefit for few …

In the large majority of cases, hepatocellular carcinoma (HCC) develops on the background
of chronic liver inflammation and fibrosis. Liver microenvironment plays a crucial role in …

Hepatocellular carcinoma (HCC) is the most common primary liver malignancy and is the
third leading cause of tumor-related mortality worldwide. In recent years, the emergency of …

According to the WHO's recently released worldwide cancer data for 2020, liver cancer
ranks sixth in morbidity and third in mortality among all malignancies. Hepatocellular …

Background: In patients with hepatocellular carcinoma (HCC), the tumor microenvironment
(TME) is resistant to immunotherapy because of its specificity. It is meaningful to explore the …