[HTML][HTML] Ethanol-mediated stress promotes autophagic survival and aggressiveness of colon cancer cells via activation of Nrf2/HO-1 pathway
C Cernigliaro, A D'Anneo, D Carlisi, M Giuliano… - Cancers, 2019 - mdpi.com
Epidemiological studies suggest that chronic alcohol consumption is a lifestyle risk factor
strongly associated with colorectal cancer development and progression. The aim of the …
strongly associated with colorectal cancer development and progression. The aim of the …
[HTML][HTML] Alteration of oxidative-stress and related marker levels in mouse colonic tissues and fecal microbiota structures with chronic ethanol administration …
H Ohira, A Tsuruya, D Oikawa, W Nakagawa… - PLoS …, 2021 - journals.plos.org
Chronic ethanol consumption is a risk factor for colorectal cancer, and ethanol-induced
reactive oxygen species have been suggested to play important roles in the pathogenesis of …
reactive oxygen species have been suggested to play important roles in the pathogenesis of …
[HTML][HTML] Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic …
K Zheng, J Yu, Z Chen, R Zhou, C Lin, Y Zhang… - …, 2019 - thelancet.com
Background Alcohol intake is a well-known lifestyle risk factor for CRC, and an increasing
number of studies have revealed that alcohol intake is also tightly associated with CRC …
number of studies have revealed that alcohol intake is also tightly associated with CRC …
[HTML][HTML] Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammation
Background Alcohol consumption is one of the major risk factors for colorectal cancer.
However, the mechanism involved in this effect of alcohol is unknown. Methods We …
However, the mechanism involved in this effect of alcohol is unknown. Methods We …
[HTML][HTML] Suppression of colonic oxidative stress caused by chronic ethanol administration and attenuation of ethanol-induced colitis and gut leakiness by oral …
H Ohira, D Oikawa, Y Kurokawa, Y Aoki, A Omura… - Food & Function, 2022 - pubs.rsc.org
Chronic consumption of excess ethanol is one of the major risk factors for colorectal cancer
(CRC), and the pathogenesis of ethanol-related CRC (ER-CRC) involves ethanol-induced …
(CRC), and the pathogenesis of ethanol-related CRC (ER-CRC) involves ethanol-induced …
[HTML][HTML] Dehydrodiisoeugenol inhibits colorectal cancer growth by endoplasmic reticulum stress-induced autophagic pathways
C Li, K Zhang, G Pan, H Ji, C Li, X Wang, X Hu… - Journal of Experimental …, 2021 - Springer
Background Dehydrodiisoeugenol (DEH), a novel lignan component extracted from nutmeg,
which is the seed of Myristica fragrans Houtt, displays noticeable anti-inflammatory and anti …
which is the seed of Myristica fragrans Houtt, displays noticeable anti-inflammatory and anti …
[HTML][HTML] Molecular basis of alcohol-related gastric and colon cancer
HK Na, JY Lee - International journal of molecular sciences, 2017 - mdpi.com
Many meta-analysis, large cohort studies, and experimental studies suggest that chronic
alcohol consumption increases the risk of gastric and colon cancer. Ethanol is metabolized …
alcohol consumption increases the risk of gastric and colon cancer. Ethanol is metabolized …
[HTML][HTML] Docosahexaenoic acid enhances oxaliplatin-induced autophagic cell death via the ER stress/Sesn2 pathway in colorectal cancer
S Jeong, DY Kim, SH Kang, HK Yun, JL Kim, BR Kim… - Cancers, 2019 - mdpi.com
Oxaliplatin is an anticancer drug administered to colorectal cancer (CRC) patients in
combination with 5-fluorouracil and antibodies (bevacizumab and cetuximab), thereby …
combination with 5-fluorouracil and antibodies (bevacizumab and cetuximab), thereby …
Quercetin protects human hepatocytes from ethanol-derived oxidative stress by inducing heme oxygenase-1 via the MAPK/Nrf2 pathways
P Yao, A Nussler, L Liu, L Hao, F Song… - Journal of …, 2007 - Elsevier
BACKGROUND/AIMS: Flavonoids, including quercetin, have been reported to have potent
hepatoprotective effects, which may be associated with HO-1 induction. However, since the …
hepatoprotective effects, which may be associated with HO-1 induction. However, since the …
[HTML][HTML] Alcohol metabolism enriches squamous cell carcinoma cancer stem cells that survive oxidative stress via autophagy
M Shimonosono, K Tanaka, S Flashner, S Takada… - Biomolecules, 2021 - mdpi.com
Background: Alcohol (ethanol) consumption is a major risk factor for head and neck and
esophageal squamous cell carcinomas (SCCs). However, how ethanol (EtOH) affects SCC …
esophageal squamous cell carcinomas (SCCs). However, how ethanol (EtOH) affects SCC …