dysfunction, decreasing the leaflet closing force, 22 as opposed to PM wall tethering.
Conceivably, however, the acute PM wall displacement in that study was insufficient to …

F unctional mitral regurgitation (MR) is frequently observed in the setting of acute myocardial
infarction or chronic heart failure. Despite extensive characterization of this phenomenon, its …

BACKGROUND Papillary muscle dysfunction (PMD) has been implicated in the
pathogenesis of ischemic mitral regurgitation (MR). We hypothesized that ischemic MR is …

The basic mechanism of ischemic mitral regurgitation (MR) is believed augmented leaflet
tethering due to the outward displacement of the papillary muscles by left ventricular (LV) …

Background Ischemic mitral regurgitation (MR) was first ascribed to papillary muscle (PM)
contractile dysfunction. Current theories include apical leaflet tethering caused by left …

Effective valve repair in patients with mitral regurgitation (MR) demands an understanding of
its mechanism. In patients with ischemic heart disease and functional MR, which doubles …

OBJECTIVES This study aimed to separate proposed mechanisms for segmental ischemic
mitral regurgitation (MR), including left ventricular (LV) dysfunction versus geometric …

Background Functional mitral regurgitation in patients with ischemic or dilated ventricles has
been related to competing factors: altered tension on the leaflets due to displacement of their …

1060 The Journal of Thoracic and Cardiovascular Surgery• December 2001 of the following
reasons:(1) simple annular dilatation (secondary to left ventricular [LV] enlargement), which …

The mechanism and temporal manifestation of functional mitral regurgitation after acute
myocardial ischemia were examined in eight dogs. Regional ischemia was produced by …