Background Depression is a seriously disabling public health problem with very high world-
wide prevalence. This study examined cross-sectional association between depression and …

Background This study aimed to determine the association between circulating leptin levels
and total depressive symptoms as well as depressive symptom dimensions (cognitive and …

Objective Animal models suggest that impaired leptin production, or leptin resistance
despite increased leptin levels, may contribute to depression. The link between leptin and …

Objective: The present study investigated whether peripheral leptin levels are associated
with current depressive episodes in a cross-sectional study nested within a population …

BACKGROUND: There is conflicting evidence regarding levels of leptin in depression. In this
study we aimed to investigate the relationship between serum leptin level and depression in …

Background Leptin is a multifunctional hormone secreted from adipose tissue, which plays a
core role in regulating energy intake and expenditure. Evidence has demonstrated that …

Aims Recent studies suggest that leptin may have an effect on emotion and mood. Low
levels of leptin in depression and anxiety have been reported in many animal models; …

Background Evidence for a role of leptin in depression is limited and conflicting.
Inconclusive findings may be explained by the complex effect of obesity on leptin signaling …

Background: Patients with bipolar disorder are at a high risk for becoming obese.
Adipokines are associated with depression and obesity via the inflammatory process …

Background Leptin and ghrelin have been implicated in the pathogenesis of major
depression. However, evidence is lacking among apparently healthy people. This study …