Malignant glioma remains the most frequent form of primary brain tumors all over the world.
The gliomagenesis is characterized by various molecular processes such as neoplastic …

Glioma is the most common primary brain tumor and is characterized by a poor prognosis.
Protein tyrosine phosphatase 1B (PTPN1), as a non‑transmembrane protein tyrosine …

OBJECTIVE: This study aims to investigate whether inflammatory response or oxidative
stress could induce upregulation of PTPN2, thus promoting the progression of …

Background PTPN3 was demonstrated to be involved in the progression of several types of
cancers, such as gastric adenocarcinoma, lung cancer, and intrahepatic …

Background Immune checkpoint inhibitors have been shown to promote antitumor immunity
and achieve durable tumor remissions. However, certain tumors are refractory to current …

The neuronal pentraxin II gene (NPTX2) is expressed in numerous tissues, such as the
pancreas and the liver. While its activity in the brain is known to be regulated by neuronal …

The underlying molecular mechanism driving clear cell renal cell carcinoma (ccRCC)
progression is still to be explored. The significant downregulation of protein tyrosine …

Background Protein tyrosine phosphatase non‐receptor type 7 (PTPN7) is a signaling
molecule that regulates a multitude of cellular processes, spanning cell proliferation, cellular …

Abstract Background Protein tyrosine phosphatases (PTPs) regulate neuronal differentiation
and survival, but their expression patterns and functions in human neuroblastoma (NB) are …

Hepatocellular carcinoma (HCC) is correlated with a poor prognosis and high mortality
worldwide. Neuronal pentraxin 1 (NPTX1) has been reported to play an oncogenic role in …