Despite the spontaneous regenerative properties of autologous bone grafts, this technique
remains dilatory and restricted to fractures and injuries. Conventional grafting strategies …

As life expectancy increases, malfunction or loss of tissue caused by injury or disease leads
to reduced quality of life in many patients at significant socioeconomic cost. Even though …

In the recent years, a paradigm shift is taking place where metallic/synthetic implants and
tissue grafts are being replaced by tissue engineering approach. A well designed three …

Synthetic polymeric scaffolds are commonly used in bone tissue engineering (BTE) due to
their biocompatibility and adequate mechanical properties. However, their hydrophobicity …

Natural bone tissue is composed of calcium-deficient carbonated hydroxyapatite as the
inorganic phase and collagen type I as the main organic phase. The biomimetic approach of …

The bone tissue engineering approach for treating large bone defects becomes necessary
when the tissue damage surpasses the threshold of the inherent regenerative ability of the …

The use of bioabsorbable polymeric scaffolds is being investigated for use in bone tissue
engineering applications, as their properties can be tailored to allow them to degrade and …

Chitosan (CS) has gained particular attention in biomedical applications due to its
biocompatibility, antibacterial feature, and biodegradability. Hence, many studies have …

Bone defects requiring grafts to promote healing are frequently occurring and costly
problems in health care. Chitosan, a biodegradable, naturally occurring polymer, has drawn …

Regeneration of craniofacial bone defects is a key issue in the bone regeneration field.
Hence, novel treatment strategies, such as tissue engineering using porous scaffolds, have …