Controlled release evaluation of paracetamol loaded amine functionalized mesoporous silica KCC1 compared to microcrystalline cellulose based tablets
M Pishnamazi, H Hafizi, M Pishnamazi, A Marjani… - Scientific reports, 2021 - nature.com
In the pharmaceutical manufacturing, drug release behavior development is remained as
one of the main challenges to improve the drug effectiveness. Recently, more focus has …
one of the main challenges to improve the drug effectiveness. Recently, more focus has …
Increasing the oral bioavailability of poorly water-soluble carbamazepine using immediate-release pellets supported on SBA-15 mesoporous silica
Z Wang, B Chen, G Quan, F Li, Q Wu… - International journal …, 2012 - Taylor & Francis
Background and methods The aim of this study was to develop an immediate-release pellet
formulation with improved drug dissolution and adsorption. Carbamazepine, a poorly water …
formulation with improved drug dissolution and adsorption. Carbamazepine, a poorly water …
A comparative study of the use of mesoporous carbon and mesoporous silica as drug carriers for oral delivery of the water-insoluble drug carvedilol
C Han, H Huang, Y Dong, X Sui, B Jian, W Zhu - Molecules, 2019 - mdpi.com
Mesoporous carriers have been extensively applied to improve the dissolution velocity and
bioavailability of insoluble drugs. The goal of this work was to compare the drug-loading …
bioavailability of insoluble drugs. The goal of this work was to compare the drug-loading …
Hollow mesoporous silica as a high drug loading carrier for regulation insoluble drug release
H Geng, Y Zhao, J Liu, Y Cui, Y Wang, Q Zhao… - International journal of …, 2016 - Elsevier
The purpose of this study was to develop a high drug loading hollow mesoporous silica
nanoparticles (HMS) and apply for regulation insoluble drug release. HMS was synthesized …
nanoparticles (HMS) and apply for regulation insoluble drug release. HMS was synthesized …
Mesoporous silica pellets–A promising oral drug delivery system?
A Szewczyk, M Prokopowicz - Journal of Drug Delivery Science and …, 2020 - Elsevier
In this study we investigated the application potential of ordered mesoporous silica SBA-15
powders as an excipient in development of prolonged release pellets for doxycycline. The …
powders as an excipient in development of prolonged release pellets for doxycycline. The …
3D cubic mesoporous silica microsphere as a carrier for poorly soluble drug carvedilol
Y Hu, Z Zhi, Q Zhao, C Wu, P Zhao, H Jiang… - Microporous and …, 2012 - Elsevier
The present work was proposed not only to exploit the potential of 3D cage-like mesoporous
silica SBA-16 with a well-defined spherical morphology as a carrier for poorly soluble drugs …
silica SBA-16 with a well-defined spherical morphology as a carrier for poorly soluble drugs …
Impact of surface area of silica particles on dissolution rate and oral bioavailability of poorly water soluble drugs: A case study with aceclofenac
D Kumar, SVS Chirravuri, NR Shastri - International Journal of …, 2014 - Elsevier
This study aims to evaluate the impact of surface area of silica particles on in vitro release of
poorly soluble drug aceclofenac and their in vivo performances. Mesoporous silicas of …
poorly soluble drug aceclofenac and their in vivo performances. Mesoporous silicas of …
Optimization of mirtazapine loaded into mesoporous silica nanostructures via Box-Behnken design: in-vitro characterization and in-vivo assessment
AA Musallam, MA Mahdy, HM Elnahas, RA Aldeeb - Drug Delivery, 2022 - Taylor & Francis
Employment of mesoporous silica nanostructures (MSNs) in the drug delivery field has
shown a significant potential for improving the oral delivery of active pharmaceutical …
shown a significant potential for improving the oral delivery of active pharmaceutical …
In vitro and in vivo evaluation of core–shell mesoporous silica as a promising water-insoluble drug delivery system: Improving the dissolution rate and bioavailability of …
C Han, S Zhang, H Huang, Y Dong, X Sui, B Jian… - Journal of …, 2019 - Elsevier
The objective of our study was to prepare mesoporous silica nanoparticles with a core–shell
structure (CSMSNs) and improve the dissolution and bioavailability of celecoxib (Cxb), a …
structure (CSMSNs) and improve the dissolution and bioavailability of celecoxib (Cxb), a …
Carboxylated mesoporous carbon microparticles as new approach to improve the oral bioavailability of poorly water-soluble carvedilol
Y Zhang, Z Zhi, X Li, J Gao, Y Song - International journal of pharmaceutics, 2013 - Elsevier
The main objective of this study was to develop carboxylated ordered mesoporous carbon
microparticles (c-MCMs) loaded with a poorly water-soluble drug, intended to be orally …
microparticles (c-MCMs) loaded with a poorly water-soluble drug, intended to be orally …