The ongoing pursuit of neuroprotective therapies in Parkinson disease
D Athauda, T Foltynie - Nature Reviews Neurology, 2015 - nature.com
Many agents developed for neuroprotective treatment of Parkinson disease (PD) have
shown great promise in the laboratory, but none have translated to positive results in …
shown great promise in the laboratory, but none have translated to positive results in …
Clinical neuroprotection in Parkinson's disease—still waiting for the breakthrough
M Löhle, H Reichmann - Journal of the neurological sciences, 2010 - Elsevier
Recent research in the pharmacotherapy of Parkinson's disease (PD) has been able to
provide numerous agents for the symptomatic control of motor impairments, but has failed to …
provide numerous agents for the symptomatic control of motor impairments, but has failed to …
Neuroprotective agents for clinical trials in Parkinson's disease: a systematic assessment
BM Ravina, SC Fagan, RG Hart, CA Hovinga… - Neurology, 2003 - AAN Enterprises
Background: Current therapies for PD ameliorate symptoms in the early phases of disease
but become less effective over time, as the underlying disease progresses. Therapies that …
but become less effective over time, as the underlying disease progresses. Therapies that …
Emerging therapies in Parkinson disease—repurposed drugs and new approaches
Parkinson disease (PD) treatment options have conventionally focused on dopamine
replacement and provision of symptomatic relief. Current treatments cause undesirable …
replacement and provision of symptomatic relief. Current treatments cause undesirable …
Promising disease-modifying therapies for Parkinson's disease
Promising disease-modifying therapies for Parkinson’s disease | Science Translational
Medicine news careers commentary Journals Science Science brought to you byGoogle Indexer …
Medicine news careers commentary Journals Science Science brought to you byGoogle Indexer …
Why have we failed to achieve neuroprotection in Parkinson's disease?
CW Olanow, K Kieburtz… - Annals of Neurology …, 2008 - Wiley Online Library
The development of a neuroprotective therapy that slows, stops, or reverses
neurodegeneration in Parkinson's disease (PD) is the single most important unresolved …
neurodegeneration in Parkinson's disease (PD) is the single most important unresolved …
Future treatments for Parkinson's disease: surfing the PD pipeline
RA Hauser - International Journal of Neuroscience, 2011 - Taylor & Francis
Our current wish list for the treatment of Parkinson's disease (PD) includes therapies that will
provide robust and sustained antiparkinsonian benefit through the day, ameliorate or …
provide robust and sustained antiparkinsonian benefit through the day, ameliorate or …
Neurobiology and treatment of Parkinson's disease
AHV Schapira - Trends in pharmacological sciences, 2009 - cell.com
Parkinson's disease (PD) is the second most common neurodegenerative disorder after
Alzheimer's disease and is an important cause of chronic disability. Numerous important …
Alzheimer's disease and is an important cause of chronic disability. Numerous important …
Pharmacological treatment of Parkinson's disease
Parkinson's disease (PD) is one of the common chronic degenerative conditions of the
nervous system. There is currently no cure for PD, but a number of drugs offer benefits in …
nervous system. There is currently no cure for PD, but a number of drugs offer benefits in …
Neuroprotective strategies for Parkinson's disease: conceptual limits of animal models and clinical trials
W Meissner, MP Hill, F Tison, CE Gross… - Trends in pharmacological …, 2004 - cell.com
Parkinson's disease (PD) is a progressive neurodegenerative disorder. Although therapies
that treat the symptoms of the disease have proven efficacy, strategies that slow or stop the …
that treat the symptoms of the disease have proven efficacy, strategies that slow or stop the …