Assessing the hepatic safety of epigallocatechin gallate (EGCG) in reproductive-aged women

H Siblini, A Al-Hendy, J Segars, F González, HS Taylor… - Nutrients, 2023 - mdpi.com
A similar abstract of the interim analysis was previously published in Fertility and Sterility.
EPIGALLOCATECHIN GALLATE (EGCG) FOR TREATMENT OF UNEXPLAINED …

Vitamin D and green tea extracts for the treatment of uterine fibroids in late reproductive life: A pilot, prospective, daily-diary based study

G Grandi, MC Del Savio, C Melotti… - Gynecological …, 2022 - Taylor & Francis
Objective The beneficial effects of Vitamin D (VD) and Epigallocatechin gallate (EGCG), a
polyphenol of green tea, on the growth of uterine fibroids (UF) were previously described in …

Antifibrotic properties of epigallocatechin-3-gallate in endometriosis

S Matsuzaki, C Darcha - Human Reproduction, 2014 - academic.oup.com
STUDY QUESTION Is epigallocatechin-3-gallate (EGCG) treatment effective in the treatment
of fibrosis in endometriosis? SUMMARY ANSWER EGCG appears to have antifibrotic …

Treatment of symptomatic uterine fibroids with green tea extract: a pilot randomized controlled clinical study

E Roshdy, V Rajaratnam, S Maitra… - … journal of women's …, 2013 - Taylor & Francis
Background Uterine fibroids (UFs, also known as leiomyoma) affect 70% of reproductive-
age women. Imposing a major burden on health-related quality-of-life (HRQL) of …

Nutraceuticals in fibroid management after ulipristal acetate administration: An observational study on patients' compliance

A Tinelli, S Gustapane, O D'Oria… - … of Gynecology & …, 2022 - Wiley Online Library
Abstract Objective On May 13, 2020, the Italian government Pharmaceutical Agency (AIFA)
stopped ulipristal acetate (UPA) treatments for uterine fibroids (UFs), so patients shifted to …

Targeting fibrotic signaling pathways by EGCG as a therapeutic strategy for uterine fibroids

MS Islam, M Parish, JT Brennan, BL Winer… - Scientific reports, 2023 - nature.com
Fibrosis is characterized by excessive accumulation of extracellular matrix, which is a key
feature of uterine fibroids. Our prior research supports the tenet that inhibition of fibrotic …

Epigallocatechin Gallate for the Treatment of Benign and Malignant Gynecological Diseases—Focus on Epigenetic Mechanisms

M Włodarczyk, M Ciebiera, G Nowicka, T Łoziński… - Nutrients, 2024 - mdpi.com
The most common malignant gynecologic diseases are cervical, uterine, ovarian, vaginal,
and vulvar cancer. Among them, ovarian cancer causes more deaths than any other cancer …

The evolving role of natural compounds in the medical treatment of uterine fibroids

M Ciebiera, M Ali, L Prince, T Jackson-Bey… - Journal of clinical …, 2020 - mdpi.com
Uterine fibroids (UFs) remain a significant health issue for many women, with a
disproportionate impact on women of color, likely due to both genetic and environmental …

[PDF][PDF] Uterine fibroids treatment: do we have new valid alternative? Experiencing the combination of vitamin D plus epigallocatechin gallate in childbearing age …

D Miriello, F Galanti, P Cignini… - European Review for …, 2021 - europeanreview.org
OBJECTIVE: Uterine myomas are the most common benign tumors in females, and at least
25% of affected patients experience symptoms severe enough to need treatment, like heavy …

Alternative oral agents in prophylaxis and therapy of uterine fibroids—an up-to-date review

M Ciebiera, K Łukaszuk, B Męczekalski… - International Journal of …, 2017 - mdpi.com
Uterine fibroids (UFs) are the most common tumors of the female genital tract. The effect of
UFs on the quality of life and the overall cost of treatment are significant issues worldwide …