NF‐κB signaling mechanisms in HTLV‐1‐induced adult T‐cell leukemia/lymphoma
The human T‐cell leukemia virus type 1 (HTLV‐1) is a complex deltaretrovirus linked to
adult T‐cell leukemia/lymphoma (ATLL), a fatal CD 4+ malignancy in 3–5% of infected …
adult T‐cell leukemia/lymphoma (ATLL), a fatal CD 4+ malignancy in 3–5% of infected …
[HTML][HTML] Mechanisms of oncogenesis by HTLV-1 Tax
The human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …
leukemia/lymphoma (ATLL), a neoplasm of CD4+ CD25+ T cells that occurs in 2–5% of …
[HTML][HTML] HTLV deregulation of the NF-κB pathway: An update on tax and antisense proteins role
S Fochi, S Mutascio, U Bertazzoni, D Zipeto… - Frontiers in …, 2018 - frontiersin.org
Human T-cell lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell
leukemia (ATL), an aggressive CD4+/CD25+ T-cell malignancy and of a severe …
leukemia (ATL), an aggressive CD4+/CD25+ T-cell malignancy and of a severe …
[HTML][HTML] Primary cells from patients with adult T cell leukemia/lymphoma depend on HTLV-1 Tax expression for NF-κB activation and survival
R Hleihel, H Skayneh, H de Thé, O Hermine… - Blood Cancer …, 2023 - nature.com
Adult T cell leukemia/lymphoma (ATL) is an aggressive malignancy secondary to chronic
infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax …
infection with human T cell leukemia virus type 1 (HTLV-1). The viral oncoprotein Tax …
Human T-cell lymphotropic virus: a model of NF-κB-associated tumorigenesis
Z Qu, G Xiao - Viruses, 2011 - mdpi.com
Human T-cell lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell
leukemia/lymphoma (ATL), whereas the highly related HTLV-2 is not associated with ATL or …
leukemia/lymphoma (ATL), whereas the highly related HTLV-2 is not associated with ATL or …
[HTML][HTML] Ubiquitination and sumoylation of the HTLV-2 Tax-2B protein regulate its NF-κB activity: a comparative study with the HTLV-1 Tax-1 protein
M Turci, J Lodewick, G Di Gennaro, AS Rinaldi… - Retrovirology, 2012 - Springer
Abstract Background Retroviruses HTLV-1 and HTLV-2 have homologous genomic
structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell …
structures but differ significantly in pathogenicity. HTLV-1 is associated with Adult T cell …
[HTML][HTML] HTLV-1 infection and adult T-cell leukemia/lymphoma—a tale of two proteins: tax and HBZ
HTLV-1 (Human T-cell lymphotropic virus type 1) is a complex human delta retrovirus that
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …
currently infects 10–20 million people worldwide. While HTLV-1 infection is generally …
Activation of NF-κB by HTLV-I and implications for cell transformation
SC Sun, S Yamaoka - Oncogene, 2005 - nature.com
T-cell transformation by the human T-cell leukemia virus type I (HTLV-I) involves
deregulation of cellular transcription factors, including members of the NF-κB family. In …
deregulation of cellular transcription factors, including members of the NF-κB family. In …
Complex cell cycle abnormalities caused by human T-lymphotropic virus type 1 Tax
L Yang, N Kotomura, YK Ho, H Zhi, S Bixler… - Journal of …, 2011 - Am Soc Microbiol
Human T-lymphotropic virus type 1 (HTLV-1) is the causative agent of adult T-cell
leukemia/lymphoma (ATL), a malignancy of CD4+ T cells whose etiology is thought to be …
leukemia/lymphoma (ATL), a malignancy of CD4+ T cells whose etiology is thought to be …
[HTML][HTML] HTLV-1 tax induces formation of the active macromolecular IKK complex by generating Lys63-and Met1-linked hybrid polyubiquitin chains
Y Shibata, F Tokunaga, E Goto, G Komatsu… - PLoS …, 2017 - journals.plos.org
The Tax protein of human T-cell leukemia virus type 1 (HTLV-1) is crucial for the
development of adult T-cell leukemia (ATL), a highly malignant CD4+ T cell neoplasm …
development of adult T-cell leukemia (ATL), a highly malignant CD4+ T cell neoplasm …