Recent updates on phytoconstituent alpha-glucosidase inhibitors: An approach towards the treatment of type two diabetes

H Kashtoh, KH Baek - Plants, 2022 - mdpi.com
Diabetes is a common metabolic disorder marked by unusually high plasma glucose levels,
which can lead to serious consequences such as retinopathy, diabetic neuropathy and …

[HTML][HTML] α-glucosidase inhibitors from plants: A natural approach to treat diabetes

S Kumar, S Narwal, V Kumar… - Pharmacognosy reviews, 2011 - ncbi.nlm.nih.gov
Diabetes is a common metabolic disease characterized by abnormally high plasma glucose
levels, leading to major complications, such as diabetic neuropathy, retinopathy, and …

Alpha glucosidase inhibitory activities of plants with focus on common vegetables

ST Assefa, EY Yang, SY Chae, M Song, J Lee, MC Cho… - Plants, 2019 - mdpi.com
Type-2 diabetes mellitus is one of the most prevalent metabolic diseases in the world, and is
characterized by hyperglycemia (ie, high levels of glucose in the blood). Alpha-glucosidases …

A review of alpha-glucosidase inhibitors from plants as potential candidates for the treatment of type-2 diabetes

AM Dirir, M Daou, AF Yousef, LF Yousef - Phytochemistry Reviews, 2022 - Springer
Diabetes mellitus is a multifactorial global health disorder that is rising at an alarming rate.
Cardiovascular diseases, kidney damage and neuropathy are the main cause of high …

Natural products as α-amylase and α-glucosidase inhibitors and their hypoglycaemic potential in the treatment of diabetes: an update

R Tundis, MR Loizzo, F Menichini - Mini reviews in medicinal …, 2010 - ingentaconnect.com
The inhibition of α-glucosidase and α-amylase, enzymes involved in the digestion of
carbohydrates, can significantly reduce the post-prandial increase of blood glucose and …

Recent advances of α-glucosidase inhibitors: A comprehensive review

N Agrawal, M Sharma, S Singh… - Current topics in …, 2022 - ingentaconnect.com
Background: Diabetes mellitus (DM) is a critical health issue prevailing in nearly half a
billion people worldwide. It is one of the most threatening metabolic diseases. Type 2 DM is …

[HTML][HTML] α-Glucosidase inhibitors isolated from medicinal plants

Z Yin, W Zhang, F Feng, Y Zhang, W Kang - Food science and human …, 2014 - Elsevier
Objective α-Glucosidase inhibitors can be used as a new class of antidiabetic drug. By
competitively inhibiting glycosidase activity, these inhibitors help to prevent the fast …

New insights into the latest advancement in α-amylase inhibitors of plant origin with anti-diabetic effects

H Kashtoh, KH Baek - Plants, 2023 - mdpi.com
The rising predominance of type 2 diabetes, combined with the poor medical effects seen
with commercially available anti-diabetic medications, has motivated the development of …

Antidiabetic medicinal plants as a source of alpha glucosidase inhibitors

W Benalla, S Bellahcen… - Current diabetes …, 2010 - ingentaconnect.com
The aim of this study is to collate all available data on antidiabetic plants that inhibit alpha
glucosidase, reported mainly by Medline (PubMed) these last years. In the present study …

Re-exploring promising α-glucosidase inhibitors for potential development into oral anti-diabetic drugs: Finding needle in the haystack

U Ghani - European journal of medicinal chemistry, 2015 - Elsevier
Abstract Treatment of diabetes mellitus by oral α-glucosidase inhibitors is currently confined
to acarbose, miglitol and voglibose marred by efficacy problems and unwanted side effects …