[HTML][HTML] Exploring the metabolic stability of engineered hairy roots after 16 years maintenance

ST Häkkinen, E Moyano, RM Cusidó… - Frontiers in Plant …, 2016 - frontiersin.org
Plants remain a major source of new drugs, leads and fine chemicals. Cell cultures deriving
from plants offer a fascinating tool to study plant metabolic pathways and offer large scale …

Hairy root research: recent scenario and exciting prospects

S Guillon, J Tremouillaux-Guiller, PK Pati… - Current opinion in plant …, 2006 - Elsevier
High stability of the production of secondary metabolites is an interesting characteristic of
hairy root cultures. For 25 years, hairy roots have been investigated as a biological system …

Hairy root cultures: a suitable biological system for studying secondary metabolic pathways in plants

P Sharma, H Padh… - Engineering in Life …, 2013 - Wiley Online Library
Hairy roots, a plant disease caused by Agrobacterium rhizogenes, show distinctive features
such as high growth rate, unlimited branching, and biochemical and genetic stability. Hairy …

Engineering secondary metabolite production in hairy roots

S Chandra, R Chandra - Phytochemistry reviews, 2011 - Springer
Plants are a rich source of valuable secondary metabolites. Plant cell culture technologies
developed in the past as possible tools for secondary metabolites production. In most cases …

Hairy root cultures for secondary metabolites production

L Pistelli, A Giovannini, B Ruffoni, A Bertoli… - Bio-farms for …, 2010 - Springer
Hairy roots (HRs) are differentiated cultures of transformed roots generated by the infection
of wounded higher plants with Agrobacterium rhizogenes. This pathogen causes the HR …

Hairy roots, their multiple applications and recent patents

MA Talano, A Laura Wevar Oller… - Recent patents on …, 2012 - ingentaconnect.com
In the last years, hairy root (HR) cultures are gaining attention in the biotechnology industry.
This particular plant cell culture derives from explants infected with Agrobacterium …

Metabolic engineering in hairy roots: An outlook on production of plant secondary metabolites

D Bagal, AA Chowdhary, S Mehrotra, S Mishra… - Plant Physiology and …, 2023 - Elsevier
Plants are one of the vital sources of secondary metabolites. These secondary metabolites
have diverse roles in human welfare, including therapeutic implication. Nevertheless …

Bioengineering hairy roots: phytoremediation, secondary metabolism, molecular pharming, plant-plant interactions and biofuels

P Habibi, MFG De Sa, A Makhzoum, S Malik… - Sustainable agriculture …, 2017 - Springer
Hairy root cultures are an efficient tool to understand plant biology, biotechnology and other
applied sciences. In particular such cultures have revealed many cues of plant cells related …

[HTML][HTML] Biotechnological exploration of transformed root culture for value-added products

M Shi, P Liao, SH Nile, MI Georgiev, G Kai - Trends in Biotechnology, 2021 - cell.com
Medicinal plants produce valuable secondary metabolites with anticancer, analgesic,
anticholinergic or other activities, but low metabolite levels and limited available tissue …

Using hairy roots for production of valuable plant secondary metabolites

L Tian - Filaments in bioprocesses, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Plants synthesize a wide variety of natural
products, which are traditionally termed secondary metabolites and, more recently, coined …