[HTML][HTML] The horizon of bone organoid: A perspective on construction and application

S Chen, X Chen, Z Geng, J Su - Bioactive Materials, 2022 - Elsevier
Bone defects repair and regeneration by various causes such as tumor resection, trauma,
degeneration, etc. have always been a key issue in the clinics. As one of the few organs that …

Bone organoids: recent advances and Future challenges

D Zhao, Q Saiding, Y Li, Y Tang… - Advanced Healthcare …, 2024 - Wiley Online Library
Bone defects stemming from tumorous growths, traumatic events, and diverse conditions
present a profound conundrum in clinical practice and research. While bone has the …

Organoids as innovative models for bone and Joint diseases

J Huang, L Zhang, A Lu, C Liang - Cells, 2023 - mdpi.com
Bone is one of the key components of the musculoskeletal system. Bone and joint disease
are the fourth most widespread disease, in addition to cardiovascular disease, cancer, and …

Hydrogels for bone organoid construction: from a materiobiological perspective

S Wu, X Wu, X Wang, J Su - Journal of Materials Science & Technology, 2023 - Elsevier
Bone organoids, which simulate and construct special organs in vitro with complex
biological functions based on tissue engineering technology, provide dramatically realistic …

Bone-targeted biomaterials: Strategies and applications

X Ren, X Chen, Z Geng, J Su - Chemical Engineering Journal, 2022 - Elsevier
Bone diseases including osteoarthritis, osteoporosis, and bone tumors are becoming severe
threats to public health. Bone-targeted biomaterials-based strategies could improve …

Bone tissue engineering scaffold materials: Fundamentals, advances, and challenges

C Xu, Z Liu, X Chen, Y Gao, W Wang, X Zhuang… - Chinese Chemical …, 2023 - Elsevier
Bone damage caused by trauma and tumors is a serious problem for human health,
therefore, three-dimensional (3D) scaffolding materials that stimulate and promote the …

Advances in Bone tissue engineering: A fundamental review

BM Manzini, LMR Machado, PY Noritomi… - Journal of …, 2021 - Springer
Bone is a dynamic tissue that can always rebuild itself by modeling and remodeling to
maintain functionality. This tissue is responsible for several vital functions in the body, such …

Study on the influence of scaffold morphology and structure on osteogenic performance

J Zhou, S Xiong, M Liu, H Yang, P Wei, F Yi… - … in Bioengineering and …, 2023 - frontiersin.org
The number of patients with bone defects caused by various bone diseases is increasing
yearly in the aging population, and people are paying increasing attention to bone tissue …

Osteogenic effects of the bioactive small molecules and minerals in the scaffold-based bone tissue engineering

B Safari, A Aghanejad, L Roshangar… - Colloids and Surfaces B …, 2021 - Elsevier
Reconstruction of the damaged bone is a striking challenge in the medical field. The bone
grafts as a current treatment is associated with inherent limitations; hence, the bone tissue …

[HTML][HTML] Bone physiological microenvironment and healing mechanism: Basis for future bone-tissue engineering scaffolds

G Zhu, T Zhang, M Chen, K Yao, X Huang, B Zhang… - Bioactive materials, 2021 - Elsevier
Bone-tissue defects affect millions of people worldwide. Despite being common treatment
approaches, autologous and allogeneic bone grafting have not achieved the ideal …