Ocular posterior segment diseases such as uveitis, X-linked juvenile retinoschisis, or age-
related macular degeneration usually result in progressive and irreversible vision loss …

Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …

Posterior eye diseases, such as age-related macular degeneration and diabetic retinopathy,
are difficult to treat due to ineffective drug delivery to affected areas. Intravitreal injection is …

Due to the unique anatomical structure of the eye, ocular drug delivery is a promising
delivery route for the treatment of several ocular diseases, such as the ocular …

A drawback in the development of treatments that can reach the retina is the presence of
barriers in the eye that restrain compounds from reaching the target. Intravitreal injections …

Purpose: Intravitreal injection of antiangiogenic agents is becoming a standard treatment for
neovascular retinal diseases. Sustained release of therapeutics by injecting colloidal …

As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

The anatomy and physiology of the eye strongly limit the bioavailability of locally
administered drugs. The entrapment of therapeutics into nanocarriers represents an …

Intravitreal injections are clinically established procedures in the treatment of posterior eye
diseases, such as wet age-related macular degeneration (wet AMD) which requires monthly …

Retinal inflammation, a common process of posterior ocular diseases, may lead to severe
vision loss or even blindness. Retinal pigment epithelium (RPE) cells are generally …