The resurgence of interest in anhedonia within major depression has been fuelled by
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …

Anhedonia is a core symptom of major depressive disorder (MDD), the neurobiological
mechanisms of which remain poorly understood. Despite decades of speculation regarding …

Anhedonia is one of the core symptoms of major depressive disorder (MDD), which is often
inadequately treated by traditional antidepressants. The modern framework of anhedonia …

Anhedonia has been implicated as a core symptom of depression and schizophrenia, and
studying anhedonia has yielded a wide array of important findings aiding the understanding …

Anhedonia has been proposed as a psychological marker for biological depression. In this
study, anhedonia was measured in a cohort of chronically depressed outpatients. Levels of …

There is an increasing heavy disease burden of major depressive disorder (MDD) globally.
Both high diagnostic heterogeneity and complicated pathological mechanisms of MDD pose …

Highlights•Discrete processes underlying anhedonia can be computationally
operationalized.•Approaches include models of reinforcement learning and effort-based …

Over the last several decades, there has been increasing interest in the role that anhedonia
plays in various psychopathologies, ranging from mood disorders, to eating disorders, to …

Background Anhedonia represents a core symptom of major depression and may be a
potential marker for melancholia. However, current understanding of this construct in …

Anhedonia, a core symptom of Major Depressive Disorder (MDD), is predictive of
antidepressant non-response. In contrast to the definition of anhedonia as a “loss of …