Maternal androgen excess increases the risk of metabolic syndrome in female offspring in their later life: A long-term population-based follow-up study

M Noroozzadeh, M Rahmati, M Farhadi-Azar… - Archives of Gynecology …, 2023 - Springer
Purpose Hyperandrogenic intrauterine environment may lead to the development of
metabolic disorders in offspring in their later life. In this study, we aimed to determine the …

Sex differences in the prenatal programming of adult metabolic syndrome by maternal androgens

G Huang, S Cherkerzian, EB Loucks… - The Journal of …, 2018 - academic.oup.com
Context Growing preclinical evidence suggests that hormonal programming by androgens in
utero may contribute to cardiovascular disease risk in adult offspring. However, the effect of …

Maternal hyperandrogenism is associated with a higher risk of type 2 diabetes mellitus and overweight in adolescent and adult female offspring: a long-term …

M Noroozzadeh, M Rahmati… - Journal of …, 2022 - Springer
Purpose Adverse intrauterine environment may predispose offspring to cardio-metabolic
dysfunction in later life. In this study, we aimed to investigate the effects of maternal …

Maternal androgen excess increases the risk of pre-diabetes mellitus in male offspring in later life: A long-term population-based follow-up study

M Farhadi-Azar, M Noroozzadeh… - Journal of …, 2023 - Springer
Purpose Prenatal androgen exposure could be a source of early programming, leading to
the development of cardiometabolic diseases in later life. In this study, we aimed to examine …

Androgenicity in young women and development of metabolic syndrome before menopause: the CARDIA and CARDIA women's studies

THT Vu, A Pirzada, CE Lewis… - Journal of the …, 2024 - academic.oup.com
Context There are no reported data from prospective long-term studies on the relation of
androgen levels in young women with development of metabolic syndrome (MetS) before …

Hyperandrogenemia is common in asymptomatic women and is associated with increased metabolic risk

LC Torchen, JN Tsai, P Jasti, R Macaya, R Sisk… - …, 2020 - Wiley Online Library
Objective Women with metabolic syndrome (MetS) have higher endogenous testosterone
(T) levels than unaffected women. This study investigated whether hyperandrogenemia (HA) …

Childbearing is associated with higher incidence of the metabolic syndrome among women of reproductive age controlling for measurements before pregnancy: the …

EP Gunderson, DR Jacobs Jr, V Chiang… - American journal of …, 2009 - Elsevier
OBJECTIVE: We sought to prospectively examine whether childbearing is associated with
higher incidence of the metabolic syndrome (MetS) after delivery among women of …

Androgen excess and post-reproductive health

SA Paschou, P Anagnostis, DG Goulis… - Maturitas, 2018 - maturitas.org
Menopause is the end of reproductive life in women, associated with a substantial decrease
in estrogen concentrations and a less intense one in androgen concentrations, resulting in a …

Relative androgen excess during the menopausal transition predicts incident metabolic syndrome in midlife women: study of Women's Health Across the Nation

JI Torrens, K Sutton-Tyrrell, X Zhao, K Matthews… - Menopause, 2009 - journals.lww.com
Objective: During the menopausal transition, total testosterone (T) remains unchanged,
whereas estrogen decreases markedly, creating a state of relative androgen excess. We …

Hyperandrogenic oligomenorrhea and metabolic risks across menopausal transition

AJ Polotsky, AA Allshouse, SL Crawford… - The Journal of …, 2014 - academic.oup.com
Context: Although there is evidence of metabolic risks in young women with irregular
menses and androgen excess, persistence of risks after menopause is unclear. Objective …