Salidroside attenuates oxidized low‑density lipoprotein‑induced endothelial cell injury via promotion of the AMPK/SIRT1 pathway

D Zhao, X Sun, S Lv, M Sun, H Guo… - International …, 2019 - spandidos-publications.com
Oxidized low‑density lipoprotein (ox‑LDL)‑induced endothelial damage contributes to the
initiation and pathogenesis of atherosclerosis. Salidroside can alleviate atherosclerosis and …

Salidroside protects against ox-LDL-induced endothelial injury by enhancing autophagy mediated by SIRT1-FoxO1 pathway

Z Zhu, J Li, X Zhang - BMC complementary and alternative medicine, 2019 - Springer
Background Atherosclerosis is a condition with the vascular accumulation of lipid plaques,
and its main major contributing factor is endothelial injury induced by oxidized low-density …

Delphinidin‐3‐glucoside protects human umbilical vein endothelial cells against oxidized low‐density lipoprotein‐induced injury by autophagy upregulation via the …

X Jin, M Chen, L Yi, H Chang, T Zhang… - Molecular nutrition & …, 2014 - Wiley Online Library
Scope Oxidized LDL (oxLDL) induced vascular endothelial cell injury is a key event in the
pathogenesis of atherosclerosis (AS). In our previous studies, we showed that delphinidin‐3 …

Puerarin protects endothelial cells from oxidized low density lipoprotein induced injuries via the suppression of LOX-1 and induction of eNOS

M Bao, Y Zhang, X Lou, Y Xiao… - Canadian Journal of …, 2014 - cdnsciencepub.com
Oxidized low density lipoprotein (oxLDL) induced injury of endothelial cells is considered to
be the first step in the pathogenesis of atherosclerosis. This study aimed to investigate some …

Schisanhenol attenuates OxLDL-induced endothelial dysfunction via an AMPK-dependent mechanism

TH Chiu, CW Ku, TJ Ho, KL Tsai, WC Hsu… - The American Journal …, 2023 - World Scientific
Atherosclerotic cardiovascular diseases, commonly known as the formation of fibrofatty
lesions in the artery wall, are the leading causes of death globally. Oxidized low-density …

Puerarin protects vascular smooth muscle cells from oxidized low‑density lipoprotein‑induced reductions in viability via inhibition of the p38 MAPK and JNK signaling …

Y Hu, H Li, R Li, Z Wu, W Yang… - Experimental and …, 2020 - spandidos-publications.com
Puerarin belongs to the family of flavonoids extracted from Pueraria lobata (Wild.) Ohwi,
which exhibits antioxidative, anti‑inflammatory, anti‑hyperglycemic, antitumor, anti …

Rosuvastatin protects against oxidized low‑density lipoprotein‑induced endothelial cell injury of atherosclerosis in vitro

J Geng, H Xu, X Yu, G Xu, H Cao… - Molecular Medicine …, 2019 - spandidos-publications.com
Atherosclerosis‑induced cardiovascular diseases (CVDs) are accompanied by substantial
morbidity and mortality. The loss and injury of endothelial cells is the primary cause of …

[HTML][HTML] Metformin regulates oxLDL-facilitated endothelial dysfunction by modulation of SIRT1 through repressing LOX-1-modulated oxidative signaling

CH Hung, SH Chan, PM Chu, HC Lin, KL Tsai - Oncotarget, 2016 - ncbi.nlm.nih.gov
It is suggested that oxLDL is decisive in the initiation and development of atherosclerotic
injuries. The up-regulation of oxidative stress and the generation of ROS act as key …

[HTML][HTML] Zedoarondiol attenuates endothelial cells injury induced by oxidized low-density lipoprotein via Nrf2 activation

H Mao, T Tao, X Wang, M Liu, D Song, X Liu… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Zedoarondiol, a sesquiterpene lactone compound, showed an anti-
proliferative activity on vascular smooth muscle cells in our previous study. However …

Myricetin ameliorates ox-LDL-induced HUVECs apoptosis and inflammation via lncRNA GAS5 upregulating the expression of miR-29a-3p

Y Bai, X Liu, Q Chen, T Chen, N Jiang, Z Guo - Scientific Reports, 2021 - nature.com
Oxidized low-density lipoprotein (ox-LDL)-induced endothelial cell dysfunction is a
significant event in the progression of atherosclerosis. Even Myricetin (Myr) has been …