Hypoxic/ischemic inflammation, microRNAs and δ-opioid receptors: hypoxia/ischemia-sensitive versus-insensitive organs

Y Chen, Y He, S Zhao, X He, D Xue… - Frontiers in Aging …, 2022 - frontiersin.org
Hypoxia and ischemia cause inflammatory injury and critically participate in the
pathogenesis of various diseases in various organs. However, the protective strategies …

δ-Opioid receptors, microRNAs, and neuroinflammation in cerebral ischemia/hypoxia

YM Chen, XZ He, SM Wang, Y Xia - Frontiers in Immunology, 2020 - frontiersin.org
Hypoxia and ischemia are the main underlying pathogenesis of stroke and other
neurological disorders. Cerebral hypoxia and/or ischemia (eg, stroke) can lead to neuronal …

δ-opioid receptor activation and microRNA expression of the rat cortex in hypoxia

Y Yang, F Zhi, X He, ML Moore, X Kang, D Chao… - PLoS …, 2012 - journals.plos.org
Prolonged hypoxic/ischemic stress may cause cortical injury and clinically manifest as a
neurological disability. Activation of the δ-opioid receptor (DOR) may induce cortical …

δ-Opioid receptor activation modified microRNA expression in the rat kidney under prolonged hypoxia

X He, Y Yang, F Zhi, ML Moore, X Kang, D Chao… - PLoS …, 2013 - journals.plos.org
Hypoxic/ischemic injury to kidney is a frequently encountered clinical problem with limited
therapeutic options. Since microRNAs are differentially involved in hypoxic/ischemic events …

[HTML][HTML] δ-Opioid receptor activation and microRNA expression in the rat heart under prolonged hypoxia

F Zhi, L Xue, N Shao, D Deng, X Kang, Y Xu… - Cellular Physiology and …, 2016 - karger.com
Background: Hypoxic/ischemic injury to the heart is a frequently encountered clinical
problem with limited therapeutic options. Since microRNAs (miRNAs) are involved in …

[HTML][HTML] Characteristic microRNA expression induced by δ-opioid receptor activation in the rat liver under prolonged hypoxia

F Zhi, N Shao, L Xue, Y Xu, X Kang, Y Yang… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Hypoxic/ischemic injury to the liver is a frequently encountered clinical
problem with limited therapeutic options. Since microRNAs (miRNAs) are involved in …

[HTML][HTML] δ-Opioid receptor, microglia and neuroinflammation

Y Xu, R Chen, F Zhi, S Sheng, L Khiati, Y Yang… - Aging and …, 2023 - ncbi.nlm.nih.gov
Neuroinflammation underlies the pathophysiology of multiple age-related neurological
disorders. Microglia, the resident immune cells of the central nervous system, are critically …

Neuroprotection against hypoxia/ischemia: δ-opioid receptor-mediated cellular/molecular events

X He, HK Sandhu, Y Yang, F Hua, N Belser… - Cellular and molecular …, 2013 - Springer
Hypoxic/ischemic injury remains the most dreaded cause of neurological disability and
mortality. Despite the humbling experiences due to lack of promising therapy, our …

Effects of hypoxia and ischemia on microRNAs in the brain

Y Yang, HK Sandhu, F Zhi, F Hua… - Current Medicinal …, 2015 - ingentaconnect.com
Hypoxia and ischemia play a major role in the pathogenesis of cerebrovascular diseases
such as stroke. However, the protective strategies against hypoxic and ischemic insults are …

The use of microRNAs to modulate redox and immune response to stroke

YB Ouyang, CM Stary, RE White… - Antioxidants & Redox …, 2015 - liebertpub.com
Significance: Cerebral ischemia is a major cause of death and disability throughout the
world, yet therapeutic options remain limited. The interplay between the cellular redox state …