High fat diet drives obesity regardless the composition of gut microbiota in mice

S Rabot, M Membrez, F Blancher, B Berger, D Moine… - Scientific reports, 2016 - nature.com
The gut microbiota is involved in many aspects of host physiology but its role in body weight
and glucose metabolism remains unclear. Here we studied the compositional changes of …

Dietary uncoupling of gut microbiota and energy harvesting from obesity and glucose tolerance in mice

MJ Dalby, AW Ross, AW Walker, PJ Morgan - Cell reports, 2017 - cell.com
Evidence suggests that altered gut microbiota composition may be involved in the
development of obesity. Studies using mice made obese with refined high-fat diets have …

Insights into the role of gut microbiota in obesity: pathogenesis, mechanisms, and therapeutic perspectives

L Sun, L Ma, Y Ma, F Zhang, C Zhao, Y Nie - Protein & cell, 2018 - academic.oup.com
Concern about health risks associated with rising obesity has become nearly universal, with
the mean body mass index (BMI) and the prevalence of obese and overweight individuals …

Long term but not short term exposure to obesity related microbiota promotes host insulin resistance

KP Foley, S Zlitni, E Denou, BM Duggan… - Nature …, 2018 - nature.com
The intestinal microbiota and insulin sensitivity are rapidly altered after ingestion of
obesogenic diets. We find that changes in the composition of the fecal microbiota precede …

Short term high fat diet induces obesity-enhancing changes in mouse gut microbiota that are partially reversed by cessation of the high fat diet

Y Shang, E Khafipour, H Derakhshani, LK Sarna… - Lipids, 2017 - Springer
The gut microbiota is proposed as a “metabolic organ” involved in energy utilization and is
associated with obesity. Dietary intervention is one of the approaches for obesity …

Replication of obesity and associated signaling pathways through transfer of microbiota from obese-prone rats

FA Duca, Y Sakar, P Lepage, F Devime, B Langelier… - Diabetes, 2014 - Am Diabetes Assoc
Aberrations in gut microbiota are associated with metabolic disorders, including obesity.
However, whether shifts in the microbiota profile during obesity are a characteristic of the …

Probiotics improve gut microbiota dysbiosis in obese mice fed a high-fat or high-sucrose diet

C Kong, R Gao, X Yan, L Huang, H Qin - Nutrition, 2019 - Elsevier
Objective Gut microbiota plays a crucial role in host energy homeostasis, which is affected
by both high-fat diets (HFDs) and high-sucrose diets (HCDs). Probiotics treatment can …

Gut microbiota-dependent modulation of energy metabolism

CN Heiss, LE Olofsson - Journal of innate immunity, 2018 - karger.com
The gut microbiota has emerged as an environmental factor that modulates the host's
energy balance. It increases the host's ability to harvest energy from the digested food, and …

High-fat diet induces dysbiosis of gastric microbiota prior to gut microbiota in association with metabolic disorders in mice

C He, D Cheng, C Peng, Y Li, Y Zhu, N Lu - Frontiers in microbiology, 2018 - frontiersin.org
Accumulating evidence suggests that high-fat diet (HFD) induced metabolic disorders are
associated with dysbiosis of gut microbiota. However, no study has explored the effect of …

High-fat feeding rather than obesity drives taxonomical and functional changes in the gut microbiota in mice

L Xiao, SB Sonne, Q Feng, N Chen, Z Xia, X Li, Z Fang… - Microbiome, 2017 - Springer
Background It is well known that the microbiota of high-fat (HF) diet-induced obese mice
differs from that of lean mice, but to what extent, this difference reflects the obese state or the …