COVID-19 is a respiratory illness caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) infection. The disease is characterized by an excessive …

Abstract Coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection has been spread around the world and is …

Strong evidence has been accumulated since the beginning of the COVID-19 pandemic that
neutrophils play an important role in the pathophysiology, particularly in those with severe …

Background: Increased inflammation is a hallmark of COVID-19, with pulmonary and
systemic inflammation identified in multiple cohorts of patients. Definitive cellular and …

Despite the introduction of vaccines, COVID-19 still affects millions of people worldwide. A
better understanding of pathophysiology and the discovery of novel therapies are needed …

Severe respiratory viral infections, including SARS-CoV-2, have resulted in high mortality
rates despite corticosteroids and other immunomodulatory therapies. Despite recognition of …

Unusually for a viral infection, the immunological phenotype of severe COVID-19 is
characterised by a depleted lymphocyte and elevated neutrophil count, with the neutrophil …

Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …

Whilst the majority of individuals infected with severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), the causative pathogen of COVID-19, experience mild to …

Neutrophils play a significant role in determining disease severity following SARS-CoV-2
infection. Gene and protein expression defines several neutrophil clusters in COVID-19 …