Cellular and systems mechanisms of memory strength as a constraint on auditory fear reconsolidation
SH Wang, L de Oliveira Alvares, K Nader - Nature neuroscience, 2009 - nature.com
Memory reconsolidation has been demonstrated in various tasks and species, suggesting it
is a fundamental process. However, there are experimental parameters that can inhibit …
is a fundamental process. However, there are experimental parameters that can inhibit …
Memory reconsolidation mediates the strengthening of memories by additional learning
JLC Lee - Nature neuroscience, 2008 - nature.com
Memories are dynamic, rather than static, in nature. The reactivation of a memory through re-
exposure to salient training stimuli results in its destabilization, necessitating a …
exposure to salient training stimuli results in its destabilization, necessitating a …
Learning and reconsolidation implicate different synaptic mechanisms
Y Li, EG Meloni, WA Carlezon Jr… - Proceedings of the …, 2013 - National Acad Sciences
Synaptic mechanisms underlying memory reconsolidation after retrieval are largely
unknown. Here we report that synapses in projections to the lateral nucleus of the amygdala …
unknown. Here we report that synapses in projections to the lateral nucleus of the amygdala …
Reactivation enables memory updating, precision-keeping and strengthening: exploring the possible biological roles of reconsolidation
Although much has been learned regarding the molecular and cellular mechanisms of
memory reconsolidation, its actual biological function remains unclear. In this work we …
memory reconsolidation, its actual biological function remains unclear. In this work we …
Increasing the GluN2A/GluN2B ratio in neurons of the mouse basal and lateral amygdala inhibits the modification of an existing fear memory trace
R Holehonnur, AJ Phensy, LJ Kim… - Journal of …, 2016 - Soc Neuroscience
Reconsolidation updating is a form of memory modification in which an existing memory can
become destabilized upon retrieval and subsequently be modified via protein-synthesis …
become destabilized upon retrieval and subsequently be modified via protein-synthesis …
Reconsolidation and the dynamic nature of memory
K Nader - Cold Spring Harbor Perspectives in Biology, 2015 - cshperspectives.cshlp.org
Memory reconsolidation is the process in which reactivated long-term memory (LTM)
becomes transiently sensitive to amnesic agents that are effective at consolidation. The …
becomes transiently sensitive to amnesic agents that are effective at consolidation. The …
Synapse-specific reconsolidation of distinct fear memories in the lateral amygdala
When reactivated, memories enter a labile, protein synthesis–dependent state, a process
referred to as reconsolidation. Here, we show in rats that fear memory retrieval produces a …
referred to as reconsolidation. Here, we show in rats that fear memory retrieval produces a …
Characterization of fear memory reconsolidation
S Duvarci, K Nader - Journal of Neuroscience, 2004 - Soc Neuroscience
Reactivation of consolidated memories returns them to a protein synthesis-dependent state.
One interpretation of these findings is that the memory reconsolidates after use. Two …
One interpretation of these findings is that the memory reconsolidates after use. Two …
Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala
Consolidation is a process through which labile memories are made persistent [Science 287
(2000) 248];[Annu Rev Psychol 55 (2004) 51]. When retrieved, a consolidated memory is …
(2000) 248];[Annu Rev Psychol 55 (2004) 51]. When retrieved, a consolidated memory is …
[HTML][HTML] Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation
J Haubrich, M Bernabo, K Nader - elife, 2020 - elifesciences.org
Memory reconsolidation is a fundamental plasticity process in the brain that allows
established memories to be changed or erased. However, certain boundary conditions limit …
established memories to be changed or erased. However, certain boundary conditions limit …