The growth of hepatocellular carcinoma (HCC) is thought to be dependent on androgens, as
androgen receptors are present in most of these tumors. The aim of this multicenter trial was …

PURPOSE The aim of the study was to evaluate the efficacy of antiandrogen therapy on
overall survival and response in unresectable hepatocellular carcinoma (HCC). PATIENTS …

The present study assessed the tumor concentration of receptors for estrogens,
progesterone and androgens in a series of Western patients with hepatocellular carcinoma …

We tested the hypothesis that a combination of sex hormone suppression and inhibition of
their target receptors might improve survival for patients with hepatocellular carcinoma …

The male preponderance in cirrhotic patients with primary hepatocellular carcinoma (HCC)
and the presence of androgen receptors in tumour tissue suggest possible benefit from anti …

Animal models of experimental liver carcinogenesis and epidemiological studies in humans
suggest a relationship between sex hormones and hepatocellular carcinoma (HCC). In …

Background & Aims: The progression of hepatocellular carcinoma may be influenced by
estrogens. This has offered the rationale for evaluating the therapeutic usefulness of …

In the past 20 years, a number of studies have investigated the relationship between sex
hormones and liver cancer. Experimental studies indicate that a dynamic process, with …

Clinical and experimental evidence indicates that estrogens are involved in the control of
hepatocyte proliferation both in normal and in neoplastic conditions. Thirty-two cirrhotic …

The liver is an estrogen responsive organ. Clinically, estrogens may play a role in the
induction of liver tumors and, experimentally, estrogens are involved in the control of …