MSCs: biological characteristics, clinical applications and their outstanding concerns

YL Si, YL Zhao, HJ Hao, XB Fu, WD Han - Ageing research reviews, 2011 - Elsevier
Mesenchymal stem cells (MSCs) are multi-potent adult stem cells harboring multi-lineage
differentiation potential and immunosuppressive properties that make MSCs an ideal …

A brief overview of global trends in MSC-based cell therapy

D Jovic, Y Yu, D Wang, K Wang, H Li, F Xu… - Stem cell reviews and …, 2022 - Springer
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

Mesenchymal stem cell senescence and rejuvenation: current status and challenges

X Zhou, Y Hong, H Zhang, X Li - Frontiers in Cell and Developmental …, 2020 - frontiersin.org
Over the past decades, mesenchymal stem cell (MSC)-based therapy has been intensively
investigated and shown promising results in the treatment of various diseases due to their …

Recent advances to enhance the immunomodulatory potential of mesenchymal stem cells

M Sarsenova, Y Kim, K Raziyeva, B Kazybay… - Frontiers in …, 2022 - frontiersin.org
Considering the unique therapeutic potential of mesenchymal stem cells (MSCs), including
their immunosuppressive and immunomodulatory properties as well as their ability to …

Mesenchymal stem cell differentiation and roles in regenerative medicine

NS Hwang, C Zhang, YS Hwang… - … : Systems Biology and …, 2009 - Wiley Online Library
Adult stem cells with multi or unipotent differentiation potential are present in almost all
tissues of adult organisms. The main function of these stem cells is to support normal repair …

Mesenchymal stem cells: Biological characteristics and application in disease therapy

S Lou, Y Duan, H Nie, X Cui, J Du, Y Yao - Biochimie, 2021 - Elsevier
Mesenchymal stem cells (MSCs) are multipotent stem cells. In addition to the capacity for
self-renewal and multipotential differentiation, MSCs also have the following characteristics …

Mesenchymal stem/progenitor cells: the prospect of human clinical translation

D Rady, MMS Abbass, AA El-Rashidy… - Stem Cells …, 2020 - Wiley Online Library
Mesenchymal stem/progenitor cells (MSCs) are key players in regenerative medicine,
relying principally on their differentiation/regeneration potential, immunomodulatory …

Potential pre-activation strategies for improving therapeutic efficacy of mesenchymal stem cells: current status and future prospects

M Li, Y Jiang, Q Hou, Y Zhao, L Zhong, X Fu - Stem cell research & …, 2022 - Springer
Mesenchymal stem cell (MSC)-based therapy has been considered as a promising
approach targeting a variety of intractable diseases due to remarkable multiple effect of …

Mesenchymal-stem-cell-based experimental and clinical trials: current status and open questions

J Wang, L Liao, J Tan - Expert opinion on biological therapy, 2011 - Taylor & Francis
Introduction: Mesenchymal stem cells (MSCs) possess remarkable self-renewal ability and
are able to differentiate into various cell lineages. MSCs can also enhance tissue repair and …

Clinical application of mesenchymal stem cell in regenerative medicine: a narrative review

R Margiana, A Markov, AO Zekiy, MU Hamza… - Stem Cell Research & …, 2022 - Springer
The multipotency property of mesenchymal stem cells (MSCs) has attained worldwide
consideration because of their immense potential for immunomodulation and their …