Branched actin filaments are found in many key cellular structures. Branches are nucleated
by the Arp2/3 complex activated by nucleation-promoting factor (NPF) proteins and bound to …

Actin branch junctions are conserved cytoskeletal elements critical for the generation of
protrusive force during actin polymerization-driven cellular motility. Assembly of actin branch …

Arp2/3 complex is an actin filament nucleation and branching machinery conserved in all
eukaryotes from yeast to human. Arp2/3 complex branched networks generate pushing …

During cellular migration, regulated actin assembly takes place at the cell leading edge, with
continuous disassembly deeper in the cell interior. Actin polymerization at the plasma …

Networks of branched actin filaments formed by Arp2/3 complex generate and experience
mechanical forces during essential cellular functions, including cell motility and endocytosis …

The Arp2/3 complex, which generates both branched but also linear actin filaments via
activation of SPIN90, is evolutionarily conserved in eukaryotes. Several factors regulate the …

Actin-related protein 2/3 complex (Arp2/3 complex) catalyzes the nucleation of branched
actin filaments that push against membranes in processes like cellular motility and …

Arp2/3 complex nucleates branched actin filaments that provide pushing forces to drive
cellular processes such as lamellipodial protrusion and endocytosis. Arp2/3 complex is …

Arp2/3 complex initiates the growth of branched actin‐filament networks by inducing actin
polymerization from the sides of pre‐existing filaments. Nucleation promoting factors (NPFs) …

Activation of the Arp2/3 complex by VCA‐motif‐bearing actin nucleation‐promoting factors
results in the formation of “daughter” actin filaments branching off the sides of pre‐existing …