Background: Until recently, the tuberculin skin test was the only test for detecting latent
tuberculosis (TB) infection, but 2 ex vivo interferon-γ release assays (IGRAs) are now …

Background: Interferon-γ–release assays (IGRAs) are alternatives to the tuberculin skin test
(TST). A recent meta-analysis showed that IGRAs have high specificity, even among …

Background Use of an interferon-γ (IFN-γ) release assay or tuberculin skin test for detection
and management of latent tuberculosis infection is controversial. For both types of test, we …

We conducted a systematic review and meta-analysis to compare the accuracy of the
QuantiFERON-TB® Gold In-Tube (QFT-G-IT) and the T-SPOT®. TB assays with the …

Background A new generation of diagnostic tests, the interferon-γ release assays (IGRAs),
have been developed for the detection of latent tuberculosis infection (LTBI). Limited data …

Rationale: Although interferon (IFN)-γ release assays are approved for the diagnosis of
latent tuberculosis infection (LTBI), limited data exist regarding their performance in HIV …

Interferon-release assays (IGRAs) represent advances in tuberculosis immunology and
evolutionary biology. IGRAs were designed to replace tuberculin skin test (TST) for the …

Identification of latent tuberculosis (TB) infection and preventive therapy is important for TB
control, especially in high-risk populations. Since the advent of interferon-γ release assays …

Interferon-γ release assays (IGRAs) are now established for the immunodiagnosis of latent
infection with Mycobacterium tuberculosis in many countries. However, the role of IGRAs for …

Background. Interferon-γ release assays (IGRAs) are attractive alternatives to the tuberculin
skin test (TST) for detecting Mycobacterium tuberculosis infection. However, the inability to …