Thimet oligopeptidase (THOP) is a cytosolic metallopeptidase known to regulate the fate of
post-proteasomal peptides, protein turnover and peptide selection in the antigen …

Thimet oligopeptidase (EC 3.4. 24.15, TOP) is a cytosolic mammalian zinc protease that can
process a diversity of bioactive peptides. TOP has been pointed out as one of the main …

Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism,
antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 …

Background The study was designed to detect the expression level of thimet oligopeptidase
(THOP1) protein in non-small cell lung cancer (NSCLC) and investigate its correlation with …

Thimet oligopeptidase (EC 3.4. 24.15; EP24. 15, THOP1) is a metallopeptidase ubiquitously
distributed in mammalian tissues. Beyond its previously well characterized role in major …

The fate of the proteasome‐generated peptides depends upon the cytosolic peptidases
whose activities ought to be regulated. One of the most important oligopeptide‐degrading …

Thimet oligopeptidase (TOP) is a zinc metallopeptidase that metabolizes a number of
bioactive peptides and degrades peptides released by the proteasome, limiting antigenic …

Peptidases generate bioactive peptides that can regulate cell signaling and mediate
intercellular communication. While the processing of peptide precursors is initiated …

Thimet oligopeptidase (TOP) is a metallopeptidase involved in the metabolism of
oligopeptides inside and outside cells of various tissues. It has been proposed that substrate …

Thimet oligopeptidase (EC 3.4. 24.15, TOP) is a metallo-oligopeptidase that participates in
the intracellular metabolism of peptides. Predictions based on structurally analogous …