Ischemic stroke is a cerebrovascular disease normally caused by interrupted blood supply to
the brain. Ischemia would initiate the cascade reaction consisted of multiple biochemical …

Ischemic stroke is still a serious threat to human life and health, but there are few therapeutic
options available to treat stroke because of limited blood-brain penetration. The …

Ischemic stroke leads to high disability and mortality. The limited delivery efficiency of most
therapeutic substances is a major challenge for effective treatment of ischemic stroke …

Cerebral ischemia is a deadly condition that arises due to blockage of the blood vessels in
the brain leading to oxygen deficiency thereby arresting brain functions and resulting in …

Owing to its intricate pathophysiology, cerebral stroke is a serious medical condition caused
by interruption or obstruction of blood supply (blockage of vasculature) to the brain tissues …

Stroke is a severe brain disease leading to disability and death. Ischemic stroke dominates
in stroke cases, and there are no effective therapies in clinic, partly due to the challenges in …

Ischemic stroke (IS) represents a significant threat to brain health due to its elevated
mortality and disability rates. The efficacy of small-molecule neuroprotective agents has …

Ischemic stroke is a vascular central nervous system (CNS) disease that leads a disability
and death. Thrombolysis and neuroprotection are the primary treatment strategies of …

Stroke is one of the major causes of death and severe disability worldwide. At present,
intravenous thrombolysis to restore blood flow at the ischemic part of the brain is the main …

From the global perspective, stroke refers to a highly common cause of disability and death.
Ischemic stroke (IS), attributed to blood vessel blockage, preventing the flow of blood to …