Objectives We recently reported that the P300 amplitude related to the Sternberg working
memory (WM) task was significantly lower in drug-naïve severe restless legs syndrome …

Objective The aim of this study was to investigate whether there is a working memory (WM)
deficit in restless legs syndrome (RLS) patients, by studying the Sternberg WM task of event …

Background: Pramipexole is a D3 dopaminergic agonist that has shown a major effect on
both sensory and motor manifestations of restless legs syndrome (RLS) in long-term trials …

In a single-blind, placebo-controlled crossover trial, the acute efficacy of the dopamine
agonist pramipexole was investigated in 11 restless legs syndrome (RLS) patients by sleep …

BACKGROUNDS: It has been reported that patients with restless legs syndrome (RLS) may
have cognitive deficit. The authors performed EEG and ERP analysis during daytime to …

OBJECTIVES: Patients with restless legs syndrome (RLS) have an elevated prevalence of
mood disorders compared with the general population. We investigated the change of RLS …

Objective: To evaluate, both polysomnographically and by subjective scales, the efficacy
and safety profile of pramipexole for restless legs syndrome (RLS) via a 3-week, double …

OBJECTIVE: To evaluate the efficacy of pramipexole on polysomnographic measures,
patient ratings and a clinical rating in Japanese patients with primary restless legs syndrome …

Background and Purpose The purpose of this study was to characterize abnormal cortical
activity during sleep in restless legs syndrome (RLS) patients and to determine the effects of …

OBJECTIVE: Dopaminergic pathways are most likely involved in the pathophysiology of
restless legs syndrome (RLS). In previous investigations, an alteration of cortical excitability …