Development of antiviral agents for enteroviruses
TC Chen, KF Weng, SC Chang, JY Lin… - Journal of …, 2008 - academic.oup.com
Enteroviruses (EVs) are common human pathogens that are associated with numerous
disease symptoms in many organ systems of the body. Although EV infections commonly …
disease symptoms in many organ systems of the body. Although EV infections commonly …
Combating enterovirus replication: state-of-the-art on antiviral research
HJ Thibaut, AM De Palma, J Neyts - Biochemical pharmacology, 2012 - Elsevier
Enteroviruses form an important genus within the large family of Picornaviridae. They are
small, non-enveloped (+) RNA viruses, many of which are important pathogens in human …
small, non-enveloped (+) RNA viruses, many of which are important pathogens in human …
Antivirals blocking entry of enteroviruses and therapeutic potential
Viruses from the genus Enterovirus (EV) of the Picornaviridae family are known to cause
diseases such as hand foot and mouth disease (HFMD), respiratory diseases, encephalitis …
diseases such as hand foot and mouth disease (HFMD), respiratory diseases, encephalitis …
[HTML][HTML] Direct-acting antivirals and host-targeting strategies to combat enterovirus infections
L Bauer, H Lyoo, HM van der Schaar… - Current opinion in …, 2017 - Elsevier
Highlights•Enteroviruses cause many human diseases, yet no antiviral drugs are
available.•Capsids and viral enzymes are promising targets for direct-acting antiviral …
available.•Capsids and viral enzymes are promising targets for direct-acting antiviral …
Direct-acting antivirals and host-targeting approaches against enterovirus B infections: recent advances
C Tammaro, M Guida, F Appetecchia, M Biava… - Pharmaceuticals, 2023 - mdpi.com
Enterovirus B (EV-B)-related diseases, which can be life threatening in high-risk
populations, have been recognized as a serious health problem, but their clinical treatment …
populations, have been recognized as a serious health problem, but their clinical treatment …
The efficacy of viral capsid inhibitors in human enterovirus infection and associated diseases
C Li, H Wang, SR Shih, TC Chen… - Current medicinal …, 2007 - ingentaconnect.com
Enteroviruses are members of picornavirus family which causes diverse and severe
diseases in humans and animals. Clinical manifestations of enterovirus infections include …
diseases in humans and animals. Clinical manifestations of enterovirus infections include …
Enteroviruses: The role of receptors in viral pathogenesis
E Heckenberg, JT Steppe, CB Coyne - Advances in Virus Research, 2022 - Elsevier
Enteroviruses are among the most common viral infectious agents of humans and cause a
broad spectrum of illness, which can range from mild and self-limiting to severe. Severe …
broad spectrum of illness, which can range from mild and self-limiting to severe. Severe …
The life cycle of non-polio enteroviruses and how to target it
J Baggen, HJ Thibaut, JRPM Strating… - Nature Reviews …, 2018 - nature.com
The genus Enterovirus (EV) of the family Picornaviridae includes poliovirus,
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
coxsackieviruses, echoviruses, numbered enteroviruses and rhinoviruses. These diverse …
The pyrimidine analog FNC potently inhibits the replication of multiple enteroviruses
N Xu, J Yang, B Zheng, Y Zhang, Y Cao… - Journal of …, 2020 - Am Soc Microbiol
Human enteroviruses (EVs), including coxsackieviruses, the numbered enteroviruses, and
echoviruses, cause a wide range of diseases, such as hand, foot, and mouth disease …
echoviruses, cause a wide range of diseases, such as hand, foot, and mouth disease …
Screening of a library of FDA-approved drugs identifies several enterovirus replication inhibitors that target viral protein 2C
R Ulferts, SM De Boer, L van Der Linden… - Antimicrobial agents …, 2016 - Am Soc Microbiol
Enteroviruses (EVs) represent many important pathogens of humans. Unfortunately, no
antiviral compounds currently exist to treat infections with these viruses. We screened the …
antiviral compounds currently exist to treat infections with these viruses. We screened the …