Bacterial pneumonia greatly contributes to the disease burden and mortality of lower
respiratory tract infections among all age groups and risk profiles. Therefore, laboratory …

Despite the need for effective treatments against chronic respiratory infections (often caused
by pathogenic biofilms), only a few new antimicrobials have been introduced to the market in …

Lower respiratory tract infections are amongst the leading causes of mortality and morbidity
worldwide. Especially in hospital settings and more particularly in critically ill ventilated …

Pneumonia is counted among the leading causes of death worldwide. Viruses, bacteria and
pathogen-related molecules interact with cells present in the human alveolus by numerous …

The human pulmonary environment is complex, containing a matrix of cells, including
fibroblasts, epithelial cells, interstitial macrophages, alveolar macrophages and neutrophils …

Pneumonia is one of the leading causes of severe and occasionally life-threatening
infections. The physiopathology of pneumonia has been extensively studied, providing …

Animal infection models play significant roles in studying bacterial pathogenic mechanisms,
host pathogen interaction as well as evaluating drug and vaccine efficacies. We have been …

Pulmonary infections have been a leading etiology of morbidity and mortality worldwide.
Upper and lower respiratory tract infections have multifactorial causes, which include …

The COVID‐19 pandemic illustrated an urgent need for sophisticated, human tissue models
to rapidly test and develop effective treatment options against this newly emerging severe …

Respiratory diseases and lower respiratory tract infections are among the leading cause of
death worldwide and, especially given the recent severe acute respiratory syndrome …