Sorafenib is the first-line chemotherapeutic therapy for advanced hepatocellular carcinoma
(HCC). However, sorafenib resistance significantly limits its therapeutic efficacy, and the …

Background and aims Accumulating evidence suggests that the primary and acquired
resistance of hepatocellular carcinoma (HCC) to sorafenib is mediated by multiple …

In recent years, circular RNAs (circRNAs) have been shown to have critical regulatory roles
in the resistance to anti-cancer drugs. However, the contributions of circRNAs to sorafenib …

Chemoresistance in hepatocellular carcinoma (HCC) has been found to be influenced by
exosomal transport of circRNAs. However, the role of circZFR in HCC chemoresistance still …

Increasing findings suggest the critical role of circular RNA (circRNA) in human cancer, and
chemotherapy resistance is a poor prognostic factor for hepatocellular carcinoma (HCC) …

Hepatocellular carcinoma (HCC) is one of the most common malignant tumors and a
leading cause of cancer-related deaths worldwide. Emerging studies have shown that …

Circular RNA (circRNA) is a novel subclass of noncoding-RNA molecules that participate in
development and progression of a variety of human diseases via sponging microRNAs …

Background Increasing evidence has revealed a close relationship between non-coding
RNAs and cancer progression. Circular RNAs (circRNAs), a recently identified new member …

Background Accumulating evidences indicate that circRNAs play important roles in the
progression and chemoresistance of human cancers. The present study is designated for …

Hepatocellular carcinoma (HCC) is one of the major causes of cancer-related death
worldwide. Circular RNAs (circRNAs), a novel class of non-coding RNA, have been reported …