The role of Interleukin 1 receptor antagonist in mesenchymal stem cell‐based tissue repair and regeneration
CR Harrell, BS Markovic, C Fellabaum… - Biofactors, 2020 - Wiley Online Library
Abstract Interleukin (IL)‐1 receptor antagonist (IL‐1Ra), a naturally occurring antagonist of IL‐
1α/IL‐1β signaling pathways, has been attributed to the immunosuppressive effects of …
1α/IL‐1β signaling pathways, has been attributed to the immunosuppressive effects of …
Mesenchymal stem cell-derived interleukin 1 receptor antagonist promotes macrophage polarization and inhibits B cell differentiation
P Luz-Crawford, F Djouad, K Toupet, C Bony… - Stem Cells, 2016 - academic.oup.com
The role of interleukin 1 receptor antagonist (IL1RA) in mediating the immunosuppressive
effect of mesenchymal stem/stromal cells (MSCs) has been reported in several studies …
effect of mesenchymal stem/stromal cells (MSCs) has been reported in several studies …
Interleukin 1 receptor antagonist mediates the antiinflammatory and antifibrotic effect of mesenchymal stem cells during lung injury
LA Ortiz, M DuTreil, C Fattman… - Proceedings of the …, 2007 - National Acad Sciences
Mesenchymal stem cells (MSCs) have been exploited as cellular vectors to treat a wide
array of diseases but the mechanisms responsible for their therapeutic effect remain …
array of diseases but the mechanisms responsible for their therapeutic effect remain …
Soluble mediators from mesenchymal stem cells suppress T cell proliferation by inducing IL-10
SH Yang, MJ Park, IH Yoon, SY Kim, SH Hong… - … & molecular medicine, 2009 - nature.com
Mesenchymal stem cells (MSCs) can inhibit T cell proliferation; however, the underlying
mechanisms are not clear. In this study, we investigated the mechanisms of the …
mechanisms are not clear. In this study, we investigated the mechanisms of the …
Interleukin-10-overexpressing mesenchymal stromal cells induce a series of regulatory effects in the inflammatory system and promote the survival of endotoxin …
C Wang, D Lv, X Zhang, Z Ni, X Sun, C Zhu - DNA and cell biology, 2018 - liebertpub.com
Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are life-threatening
inflammatory conditions with no effective pharmacological treatment. Previous studies …
inflammatory conditions with no effective pharmacological treatment. Previous studies …
Concise review: mesenchymal stem cells and translational medicine: emerging issues
Mesenchymal stem cells (MSCs) are emerging as a promising therapeutic approach of cell-
based therapy for a wide range of autoimmune disorders and degenerative diseases. In …
based therapy for a wide range of autoimmune disorders and degenerative diseases. In …
The interaction between mesenchymal stem cells and steroids during inflammation
Mesenchymal stem cells (MSCs) are believed to exert their regenerative effects through
differentiation and modulation of inflammatory responses. However, the relationship …
differentiation and modulation of inflammatory responses. However, the relationship …
IL‐10 gene‐modified human amniotic mesenchymal stem cells augment regenerative wound healing by multiple synergistic effects
S Xiao, G Huang, Z Wei, K Nie, Z Liu… - Stem Cells …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) possess a capacity to enhance cutaneous wound healing
that is well characterized. However, the therapeutic effect of MSCs appears to be limited …
that is well characterized. However, the therapeutic effect of MSCs appears to be limited …
Interleukin (IL)-10 Induced by CD11b+ Cells and IL-10-Activated Regulatory T Cells Play a Role in Immune Modulation of Mesenchymal Stem Cells in Rat Islet …
YH Kim, YM Wee, MY Choi, DG Lim, SC Kim… - Molecular Medicine, 2011 - Springer
Mesenchymal stem cells (MSCs) are suggested to be immune modulators because of their
therapeutic potential in transplantation. In the present study, we evaluated the therapeutic …
therapeutic potential in transplantation. In the present study, we evaluated the therapeutic …
Mesenchymal stem cells attenuate liver fibrosis by suppressing Th17 cells–an experimental study
N Milosavljevic, M Gazdic… - Transplant …, 2018 - Wiley Online Library
This study investigates molecular and cellular mechanisms involved in mesenchymal stem
cell (MSC)‐mediated modulation of IL‐17 signaling during liver fibrosis. Mice received CC l4 …
cell (MSC)‐mediated modulation of IL‐17 signaling during liver fibrosis. Mice received CC l4 …
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