[HTML][HTML] Enabling accelerated vaccine roll-out for public health emergencies of international concern (PHEICs): novel oral polio vaccine type 2 (nOPV2) experience

GR Macklin, C Peak, M Eisenhawer, F Kurji, O Mach… - Vaccine, 2023 - Elsevier
To address the evolving risk of circulating vaccine-derived poliovirus type 2 (cVDPV2),
Global Polio Eradication Initiative (GPEI) partners are working closely with countries to …

[DOC][DOC] Trivalent oral polio vaccine (tOPV) request form: for response to type 2 vaccine-derived poliovirus (VDPV2) and type 2 wild poliovirus (WPV2)

World Health Organization - 2020 - apps.who.int
Following global withdrawal of oral polio vaccine type 2 (OPV2) from national immunization
programmes in 2016, a confirmed type 2 event will be considered a public health …

Assessment of serological responses following vaccination campaigns with type 2 novel oral polio vaccine: a population-based study in Tajikistan in 2021

A Mirzoev, GR Macklin, Y Zhang, BA Mainou… - The Lancet Global …, 2022 - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) was used to control an outbreak
of type 2 circulating vaccine derived poliovirus (cVDPV2) in Tajikistan, in 2021. We …

[HTML][HTML] Serotype 2 oral poliovirus vaccine (OPV2) choices and the consequences of delaying outbreak response

DA Kalkowska, MA Pallansch, SGF Wassilak, SL Cochi… - Vaccine, 2023 - Elsevier
Abstract The Global Polio Eradication Initiative (GPEI) faces substantial challenges with
managing outbreaks of serotype 2 circulating vaccine-derived polioviruses (cVDPV2s) in …

[HTML][HTML] Outbreak response strategies with type 2-containing oral poliovirus vaccines

DA Kalkowska, SGF Wassilak, MA Pallansch… - Vaccine, 2023 - Elsevier
Despite exhaustive and fully-financed plans to manage the risks of globally coordinated
cessation of oral poliovirus vaccine (OPV) containing type 2 (OPV2) prior to 2016, as of …

[HTML][HTML] Genetic characterization of novel oral polio vaccine type 2 viruses during initial use phase under emergency use listing—worldwide, March–October 2021

J Martin - MMWR. Morbidity and Mortality Weekly Report, 2022 - cdc.gov
Discussion The most consequential risks known to be associated with use of live attenuated
Sabin OPVs include the emergence of VDPVs resulting from reversion to neurovirulence …

One billion doses and WHO prequalification of nOPV2: implications for the global polio situation and beyond

AS Bandyopadhyay, LV Cooper… - PLOS Global Public …, 2024 - journals.plos.org
With the COVID-19 pandemic abating, the only remaining Public Health Emergency of
International Concern is polio [1]. Remarkable progress has been made in reducing the …

A novel tool to eradicate an ancient scourge: the novel oral polio vaccine type 2 story

AS Bandyopadhyay, S Zipursky - The Lancet Infectious Diseases, 2023 - thelancet.com
The recent detection of vaccine-derived poliovirus (VDPV) in London (UK) and a case of
paralytic polio in New York (USA) have highlighted how the scourge of poliomyelitis has not …

Poliovirus antibodies following two rounds of campaigns with a type 2 novel oral poliovirus vaccine in Liberia: a clustered, population-based seroprevalence survey

SB Kennedy, GR Macklin, GM Ross… - The Lancet Global …, 2023 - thelancet.com
Background Novel oral poliovirus vaccine type 2 (nOPV2) was administered in Liberia in
response to an outbreak of circulating vaccine-derived poliovirus type 2 (cVDPV2) in 2021 …

[HTML][HTML] Cessation of trivalent oral poliovirus vaccine and introduction of inactivated poliovirus vaccine—worldwide, 2016

LM Hampton - MMWR. Morbidity and Mortality Weekly Report, 2016 - cdc.gov
To address the risks posed by type 2 circulating vaccine-derived polioviruses, which have
caused hundreds of paralytic poliomyelitis cases since 2006, the type 2 component of oral …