Human fungal pathogens are a deadly and underappreciated risk to global health that most
severely affect immunocompromised individuals. A virulence attribute shared by some of the …

Fungal diseases contribute significantly to morbidity and mortality in humans. Although
recent research has improved our understanding of the complex and dynamic interplay that …

Fungal infections represent a major, albeit neglected, public health threat with serious
medical and economic burdens globally. With unacceptably high mortality rates, invasive …

Fungal infections are a cause of morbidity in humans, and despite the availability of a range
of antifungal treatments, the mortality rate remains unacceptably high. Although our …

Human fungal infections are a historically neglected area of disease research, yet they
cause more than 1.5 million deaths every year. Our understanding of the pathophysiology of …

Fungal diseases are major causes of morbidity and mortality among the
immunocompromised, including HIV-infected individuals and patients with cancer …

Invasive fungal infections pose a major threat to human health. Bacterial and protozoan
pathogens secrete protein effectors that overcome innate immune barriers to promote …

A successful pathogen is one that is able to effectively survive and evade detection by the
host innate immune defense. Fungal pathogens have adopted strategies which evade host …

Life-threatening fungal infections have risen sharply in recent years, owing to the advances
and intensity of medical care that may blunt immunity in patients. This emerging crisis has …

Fungal pathogenesis is by definition a situation in which a fungal species is successfully
surviving in host tissues and causing local destruction or toxicity. The immune system is …