[HTML][HTML] Molecularly defined and spatially resolved cell atlas of the whole mouse brain

M Zhang, X Pan, W Jung, AR Halpern, SW Eichhorn… - Nature, 2023 - nature.com
In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …

[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain

Z Yao, CTJ van Velthoven, M Kunst, M Zhang… - Nature, 2023 - nature.com
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

[HTML][HTML] The molecular cytoarchitecture of the adult mouse brain

J Langlieb, NS Sachdev, KS Balderrama, NM Nadaf… - Nature, 2023 - nature.com
The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …

[HTML][HTML] Spatial atlas of the mouse central nervous system at molecular resolution

H Shi, Y He, Y Zhou, J Huang, K Maher, B Wang… - Nature, 2023 - nature.com
Spatially charting molecular cell types at single-cell resolution across the 3D volume is
critical for illustrating the molecular basis of brain anatomy and functions. Single-cell RNA …

[HTML][HTML] Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics

M Ratz, L von Berlin, L Larsson, M Martin… - Nature …, 2022 - nature.com
The mammalian brain contains many specialized cells that develop from a thin sheet of
neuroepithelial progenitor cells. Single-cell transcriptomics revealed hundreds of …

Genome-wide atlas of gene expression in the adult mouse brain

ES Lein, MJ Hawrylycz, N Ao, M Ayres, A Bensinger… - Nature, 2007 - nature.com
Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …

Spatially resolved transcriptomics in neuroscience

JL Close, BR Long, H Zeng - Nature methods, 2021 - nature.com
One major challenge in neuroscience is to gain a systematic understanding of the
extraordinary diversity of brain cell types and how they contribute to brain function. Spatially …

[HTML][HTML] Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH

M Zhang, SW Eichhorn, B Zingg, Z Yao, K Cotter… - Nature, 2021 - nature.com
A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …

[HTML][HTML] A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex

Z Yao, H Liu, F Xie, S Fischer, RS Adkins, AI Aldridge… - Nature, 2021 - nature.com
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …

The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing

E Lein, LE Borm, S Linnarsson - Science, 2017 - science.org
The stereotyped spatial architecture of the brain is both beautiful and fundamentally related
to its function, extending from gross morphology to individual neuron types, where soma …