[HTML][HTML] Molecularly defined and spatially resolved cell atlas of the whole mouse brain
In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …
a wide range of functions. The enormous diversity and intricate organization of cells have …
[HTML][HTML] A high-resolution transcriptomic and spatial atlas of cell types in the whole mouse brain
The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …
types with specific spatial distribution patterns and structural and functional properties …
[HTML][HTML] The molecular cytoarchitecture of the adult mouse brain
J Langlieb, NS Sachdev, KS Balderrama, NM Nadaf… - Nature, 2023 - nature.com
The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …
diversely specialized cell types. Yet, the molecular identities of the cell types and their …
[HTML][HTML] Spatial atlas of the mouse central nervous system at molecular resolution
Spatially charting molecular cell types at single-cell resolution across the 3D volume is
critical for illustrating the molecular basis of brain anatomy and functions. Single-cell RNA …
critical for illustrating the molecular basis of brain anatomy and functions. Single-cell RNA …
[HTML][HTML] Clonal relations in the mouse brain revealed by single-cell and spatial transcriptomics
The mammalian brain contains many specialized cells that develop from a thin sheet of
neuroepithelial progenitor cells. Single-cell transcriptomics revealed hundreds of …
neuroepithelial progenitor cells. Single-cell transcriptomics revealed hundreds of …
Genome-wide atlas of gene expression in the adult mouse brain
ES Lein, MJ Hawrylycz, N Ao, M Ayres, A Bensinger… - Nature, 2007 - nature.com
Molecular approaches to understanding the functional circuitry of the nervous system
promise new insights into the relationship between genes, brain and behaviour. The cellular …
promise new insights into the relationship between genes, brain and behaviour. The cellular …
Spatially resolved transcriptomics in neuroscience
One major challenge in neuroscience is to gain a systematic understanding of the
extraordinary diversity of brain cell types and how they contribute to brain function. Spatially …
extraordinary diversity of brain cell types and how they contribute to brain function. Spatially …
[HTML][HTML] Spatially resolved cell atlas of the mouse primary motor cortex by MERFISH
A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …
[HTML][HTML] A transcriptomic and epigenomic cell atlas of the mouse primary motor cortex
Single-cell transcriptomics can provide quantitative molecular signatures for large, unbiased
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …
samples of the diverse cell types in the brain,–. With the proliferation of multi-omics datasets …
The promise of spatial transcriptomics for neuroscience in the era of molecular cell typing
The stereotyped spatial architecture of the brain is both beautiful and fundamentally related
to its function, extending from gross morphology to individual neuron types, where soma …
to its function, extending from gross morphology to individual neuron types, where soma …