Design, optimization, and nanotechnology of antimicrobial peptides: From exploration to applications

P Tan, H Fu, X Ma - Nano Today, 2021 - Elsevier
Antibiotic resistance caused by antibiotic abuse, especially the emergence of multi-drug
resistant bacteria, poses a serious threat to human health, and makes it imperative to find …

Role and modulation of the secondary structure of antimicrobial peptides to improve selectivity

Y Liang, X Zhang, Y Yuan, Y Bao, M Xiong - Biomaterials Science, 2020 - pubs.rsc.org
Since the development of bacterial resistance, the decreasing effectiveness of antibiotics is
becoming one of the most critical problems worldwide. Novel antibacterial agents are …

Nanostructured antimicrobial peptides: The last push towards clinics

JV Carratalá, N Serna, A Villaverde, E Vázquez… - Biotechnology …, 2020 - Elsevier
Peptide drugs hold great potential for the treatment of infectious diseases due to their
unconventional mechanisms of action, biocompatibility, biodegradability and ease of …

[HTML][HTML] Molecular engineering of antimicrobial peptides: Microbial targets, peptide motifs and translation opportunities

P Cardoso, H Glossop, TG Meikle, A Aburto-Medina… - Biophysical …, 2021 - Springer
The global public health threat of antimicrobial resistance has led the scientific community to
highly engage into research on alternative strategies to the traditional small molecule …

Enhancing the stability of antimicrobial peptides: From design strategies to biomedical applications

S Xu, P Tan, Q Tang, T Wang, Y Ding, H Fu… - Chemical Engineering …, 2023 - Elsevier
Antimicrobial peptides (AMPs) offer unique advantages due to their membrane-active
antimicrobial mechanisms, which reduce the likelihood of resistance development …

Antimicrobial polymers as synthetic mimics of host‐defense peptides

K Kuroda, GA Caputo - Wiley Interdisciplinary Reviews …, 2013 - Wiley Online Library
Antibiotic‐resistant bacteria 'superbugs' are an emerging threat to public health due to the
decrease in effective antibiotics as well as the slowed pace of development of new …

Tailoring supramolecular short peptide nanomaterials for antibacterial applications

M Abbas, M Ovais, A Atiq, TM Ansari, R Xing… - Coordination Chemistry …, 2022 - Elsevier
The rise of bacterial resistance to current antibiotics poses a threat to humanity and
reinforces the need for new-generation nanomaterials with antibacterial properties and …

Synthetic biology and computer-based frameworks for antimicrobial peptide discovery

MDT Torres, J Cao, OL Franco, TK Lu… - ACS …, 2021 - ACS Publications
Antibiotic resistance is one of the greatest challenges of our time. This global health problem
originated from a paucity of truly effective antibiotic classes and an increased incidence of …

[HTML][HTML] Antimicrobial peptide polymers: No escape to ESKAPE pathogens—A review

S Mukhopadhyay, AS Bharath Prasad… - World Journal of …, 2020 - Springer
Antimicrobial resistance (AMR) is one of the significant clinical challenges and also an
emerging area of concern arising from nosocomial infections of ESKAPE pathogens, which …

[HTML][HTML] Antimicrobial peptides as anti-infective agents in pre-post-antibiotic era?

T Rončević, J Puizina, A Tossi - International journal of molecular …, 2019 - mdpi.com
Resistance to antibiotics is one of the main current threats to human health and every year
multi-drug resistant bacteria are infecting millions of people worldwide, with many dying as a …