[HTML][HTML] Anticancer effects and molecular action of 7-α-hydroxyfrullanolide in G2/M-phase arrest and apoptosis in triple negative breast cancer cells
Triple negative breast cancer (TNBC) is a breast cancer subtype characterized by the
absence of estrogen receptor, progesterone receptor and human epidermal growth factor …
absence of estrogen receptor, progesterone receptor and human epidermal growth factor …
[HTML][HTML] 5, 6, 7, 3', 4', 5'-Hexamethoxyflavone inhibits growth of triple-negative breast cancer cells via suppression of MAPK and Akt signaling pathways and arresting …
N Borah, S Gunawardana… - International …, 2017 - spandidos-publications.com
Natural components continue to be an important source for the discovery and development
of novel anticancer agents. Polymethoxyflavones are a class of flavonoids found in citrus …
of novel anticancer agents. Polymethoxyflavones are a class of flavonoids found in citrus …
Small-molecule inhibitor of Fam20C in combination with paclitaxel suppresses tumor growth by LIF-JAK2/STAT3-modulated apoptosis in triple-negative breast cancer
Z Yuan, Y Zhen, S Chen, Z Li, L Fu - Journal of the Taiwan Institute of …, 2023 - Elsevier
Background Triple negative breast cancer (TNBC) is a strongly proliferative, relapse prone,
high-mortality subtype of breast cancer. Due to the lack of effective therapeutic targets, the …
high-mortality subtype of breast cancer. Due to the lack of effective therapeutic targets, the …
[HTML][HTML] Benzo[f]indole-4,9-dione Derivatives Effectively Inhibit the Growth of Triple-Negative Breast Cancer
FS Guerra, FRF Dias, AC Cunha, PD Fernandes - Molecules, 2021 - mdpi.com
Triple-negative breast cancer (TNBC) is a subtype of breast cancer with poor clinical
outcome, and currently no effective targeted therapies are available. Indole compounds …
outcome, and currently no effective targeted therapies are available. Indole compounds …
Growth inhibition, G1-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives
JA Marchal, H Boulaiz, I Suárez, E Saniger… - Investigational new …, 2004 - Springer
In this study we evaluate the antitumour activity, the cell cycle arrest and apoptotic properties
of novel lipophilic benzene-fused seven-membered 5-fluorouracil (5-FU) analogs in …
of novel lipophilic benzene-fused seven-membered 5-fluorouracil (5-FU) analogs in …
[HTML][HTML] Anti‑breast cancer potential of frullanolide from Grangea maderaspatana plant by inducing apoptosis
S Chimplee, P Graidist, T Srisawat… - Oncology …, 2019 - spandidos-publications.com
Breast cancer is the leading cause of female mortality worldwide. Although there are several
modern treatments for breast cancer, there is a high rate of recurrence for the majority of …
modern treatments for breast cancer, there is a high rate of recurrence for the majority of …
[HTML][HTML] Arnicolide D inhibits triple negative breast cancer cell proliferation by suppression of Akt/mTOR and STAT3 signaling pathways
Z Qu, Y Lin, DKW Mok, Q Bian, WCS Tai… - International Journal of …, 2020 - ncbi.nlm.nih.gov
Abstract Triple-Negative Breast Cancer (TNBC) is a most dangerous breast cancer subtype.
The naturally occurring sesquiterpene lactone, arnicolide D (AD), has proven effective …
The naturally occurring sesquiterpene lactone, arnicolide D (AD), has proven effective …
[HTML][HTML] Anticancer effects of fucoxanthin through cell cycle arrest, apoptosis induction, and angiogenesis inhibition in triple-negative breast cancer cells
SA Ahmed, P Mendonca, SS Messeha, KFA Soliman - Molecules, 2023 - mdpi.com
The absence of progesterone receptors, estrogen receptors, and human epidermal growth
factor receptor-2 restricts the therapy choices for treating triple-negative breast cancer …
factor receptor-2 restricts the therapy choices for treating triple-negative breast cancer …
[HTML][HTML] Anti-cancer effect of a phytochemical compound–7R-acetylmelodorinol–against triple-negative breast cancer cells
C Thepmalee, N Sawasdee, P Jenkham… - Biomedicine & …, 2023 - Elsevier
Triple-negative breast cancer (TNBC) is a highly aggressive subtype currently lacking
effective treatment options. Consequently, novel and effective drugs or compounds are …
effective treatment options. Consequently, novel and effective drugs or compounds are …
Indole-2-carboxamide derivative LG25 inhibits triple-negative breast cancer growth by suppressing akt/mTOR/NF-κB signalling pathway
X Xu, V Rajamanickam, S Shu, Z Liu… - Drug Design …, 2019 - Taylor & Francis
Background Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer
which is associated with poor patient outcome and lack of targeted therapy. Our laboratory …
which is associated with poor patient outcome and lack of targeted therapy. Our laboratory …