Thiazole-containing compounds as therapeutic targets for cancer therapy
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …
development, and several new anticancer agents of natural and synthetic origin have been …
Thiazole in the targeted anticancer drug discovery
Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …
Thiadiazole derivatives as anticancer agents
M Szeliga - Pharmacological Reports, 2020 - Springer
In spite of substantial progress made toward understanding cancer pathogenesis, this
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …
Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery
SR Alizadeh, SM Hashemi - Medicinal Chemistry Research, 2021 - Springer
Currently, the development of anticancer drug resistance is significantly restricted the clinical
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …
2-Aminothiazole: A privileged scaffold for the discovery of anti-cancer agents
Y Wan, J Long, H Gao, Z Tang - European Journal of Medicinal Chemistry, 2021 - Elsevier
Cancer has been the second heath killer being next only to cardiovascular diseases in
human society. Although many efforts have been taken for cancer therapy and many …
human society. Although many efforts have been taken for cancer therapy and many …
Recent patents on thiazole derivatives endowed with antitumor activity
R Morigi, A Locatelli, A Leoni… - Recent patents on anti …, 2015 - ingentaconnect.com
Cancer is a disease of remarkable importance in the world today and is projected to become
the primary cause of death within the coming years, therefore the design and development …
the primary cause of death within the coming years, therefore the design and development …
Anticancer potential of thiazole derivatives: a retrospective review
S Jain, S Pattnaik, K Pathak, S Kumar… - Mini reviews in …, 2018 - ingentaconnect.com
This review brings forth the potential of thiazole derivatives for their anticancer activities. The
emphasis is placed on the structural diversity of thiazole derivatives, responsible for their …
emphasis is placed on the structural diversity of thiazole derivatives, responsible for their …
A review on anticancer potentials of benzothiazole derivatives
Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …
imparts a broad spectrum of biological activities to it. The significant and potent activity of …
Application and synthesis of thiazole ring in clinically approved drugs
ZX Niu, YT Wang, SN Zhang, Y Li, XB Chen… - European Journal of …, 2023 - Elsevier
The development of heterocyclic derivatives has progressed considerably over the past few
decades, and many new agents of synthetic and natural origin have been produced. Among …
decades, and many new agents of synthetic and natural origin have been produced. Among …
5-(Thiophen-2-yl)-1, 3, 4-thiadiazole derivatives: Synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents
SM Gomha, MM Edrees, ZA Muhammad… - Drug Design …, 2018 - Taylor & Francis
Background Nowadays, cancer is an important public health problem in all countries.
Limitations of current chemotherapy for neoplastic diseases such as severe adverse …
Limitations of current chemotherapy for neoplastic diseases such as severe adverse …