Thiazole-containing compounds as therapeutic targets for cancer therapy

PC Sharma, KK Bansal, A Sharma, D Sharma… - European journal of …, 2020 - Elsevier
In the last few decades, considerable progress has been made in anticancer agents
development, and several new anticancer agents of natural and synthetic origin have been …

Thiazole in the targeted anticancer drug discovery

A Ayati, S Emami, S Moghimi… - Future medicinal …, 2019 - Future Science
Cancer is known as one of the main causes of death in the world; and many compounds
have been synthesized to date with potential use in cancer therapy. Thiazole is a versatile …

Thiadiazole derivatives as anticancer agents

M Szeliga - Pharmacological Reports, 2020 - Springer
In spite of substantial progress made toward understanding cancer pathogenesis, this
disease remains one of the leading causes of mortality. Thus, there is an urgent need to …

Development and therapeutic potential of 2-aminothiazole derivatives in anticancer drug discovery

SR Alizadeh, SM Hashemi - Medicinal Chemistry Research, 2021 - Springer
Currently, the development of anticancer drug resistance is significantly restricted the clinical
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …

2-Aminothiazole: A privileged scaffold for the discovery of anti-cancer agents

Y Wan, J Long, H Gao, Z Tang - European Journal of Medicinal Chemistry, 2021 - Elsevier
Cancer has been the second heath killer being next only to cardiovascular diseases in
human society. Although many efforts have been taken for cancer therapy and many …

Recent patents on thiazole derivatives endowed with antitumor activity

R Morigi, A Locatelli, A Leoni… - Recent patents on anti …, 2015 - ingentaconnect.com
Cancer is a disease of remarkable importance in the world today and is projected to become
the primary cause of death within the coming years, therefore the design and development …

Anticancer potential of thiazole derivatives: a retrospective review

S Jain, S Pattnaik, K Pathak, S Kumar… - Mini reviews in …, 2018 - ingentaconnect.com
This review brings forth the potential of thiazole derivatives for their anticancer activities. The
emphasis is placed on the structural diversity of thiazole derivatives, responsible for their …

A review on anticancer potentials of benzothiazole derivatives

N Pathak, E Rathi, N Kumar, SG Kini… - Mini reviews in …, 2020 - ingentaconnect.com
Benzothiazole is an organic compound bearing a heterocyclic nucleus (thiazole) which
imparts a broad spectrum of biological activities to it. The significant and potent activity of …

Application and synthesis of thiazole ring in clinically approved drugs

ZX Niu, YT Wang, SN Zhang, Y Li, XB Chen… - European Journal of …, 2023 - Elsevier
The development of heterocyclic derivatives has progressed considerably over the past few
decades, and many new agents of synthetic and natural origin have been produced. Among …

5-(Thiophen-2-yl)-1, 3, 4-thiadiazole derivatives: Synthesis, molecular docking and in vitro cytotoxicity evaluation as potential anticancer agents

SM Gomha, MM Edrees, ZA Muhammad… - Drug Design …, 2018 - Taylor & Francis
Background Nowadays, cancer is an important public health problem in all countries.
Limitations of current chemotherapy for neoplastic diseases such as severe adverse …