Advances and utility of the human plasma proteome

EW Deutsch, GS Omenn, Z Sun, M Maes… - Journal of proteome …, 2021 - ACS Publications
The study of proteins circulating in blood offers tremendous opportunities to diagnose,
stratify, or possibly prevent diseases. With recent technological advances and the urgent …

The human plasma proteome draft of 2017: building on the human plasma PeptideAtlas from mass spectrometry and complementary assays

JM Schwenk, GS Omenn, Z Sun… - Journal of proteome …, 2017 - ACS Publications
Human blood plasma provides a highly accessible window to the proteome of any individual
in health and disease. Since its inception in 2002, the Human Proteome Organization's …

Clinical applications of plasma proteomics and peptidomics: Towards precision medicine

B He, Z Huang, C Huang… - PROTEOMICS–Clinical …, 2022 - Wiley Online Library
In the context of precision medicine, disease treatment requires individualized strategies
based on the underlying molecular characteristics to overcome therapeutic challenges …

State of the human proteome in 2013 as viewed through PeptideAtlas: comparing the kidney, urine, and plasma proteomes for the biology-and disease-driven Human …

T Farrah, EW Deutsch, GS Omenn, Z Sun… - Journal of proteome …, 2014 - ACS Publications
The kidney, urine, and plasma proteomes are intimately related: proteins and metabolic
waste products are filtered from the plasma by the kidney and excreted via the urine, while …

Mass spectrometry-based plasma proteomics: considerations from sample collection to achieving translational data

V Ignjatovic, PE Geyer, KK Palaniappan… - Journal of proteome …, 2019 - ACS Publications
The proteomic analysis of human blood and blood-derived products (eg, plasma) offers an
attractive avenue to translate research progress from the laboratory into the clinic. However …

Progress on identifying and characterizing the human proteome: 2018 metrics from the HUPO human proteome project

GS Omenn, L Lane, CM Overall… - Journal of proteome …, 2018 - ACS Publications
The Human Proteome Project (HPP) annually reports on progress throughout the field in
credibly identifying and characterizing the human protein parts list and making proteomics …

HBFP: a new repository for human body fluid proteome

D Shao, L Huang, Y Wang, X Cui, Y Li, Y Wang… - Database, 2021 - academic.oup.com
Body fluid proteome has been intensively studied as a primary source for disease biomarker
discovery. Using advanced proteomics technologies, early research success has resulted in …

[HTML][HTML] Plasma proteome profiling to assess human health and disease

PE Geyer, NA Kulak, G Pichler, LM Holdt, D Teupser… - Cell systems, 2016 - cell.com
Proteins in the circulatory system mirror an individual's physiology. In daily clinical practice,
protein levels are generally determined using single-protein immunoassays. High …

Progress on the HUPO draft human proteome: 2017 metrics of the human proteome project

GS Omenn, L Lane, EK Lundberg… - Journal of proteome …, 2017 - ACS Publications
The Human Proteome Organization (HUPO) Human Proteome Project (HPP) continues to
make progress on its two overall goals:(1) completing the protein parts list, with an annual …

Plasma Proteome Database as a resource for proteomics research: 2014 update

V Nanjappa, JK Thomas, A Marimuthu… - Nucleic acids …, 2014 - academic.oup.com
Abstract Plasma Proteome Database (PPD; http://www. plasmaproteomedatabase. org/) was
initially described in the year 2005 as a part of Human Proteome Organization's (HUPO's) …