Fragmentation of DMPC Membranes by a Wedge-Shaped Amphiphilic Cyclodextrin into Bicellar-like Aggregates

M Roux, FX Legrand, A Bil, V Bonnet… - The Journal of …, 2023 - ACS Publications
Small bilayer lipid aggregates such as bicelles provide useful isotropic or anisotropic
membrane mimetics for structural studies of biological membranes. We have shown …

[PDF][PDF] Cyclodextrin-induced lipid lateral separation in DMPC membranes: 2H nuclear magnetic resonance study

M Roux, R Auzely-Velty, F Djedaini-Pilard, B Perly - Biophysical journal, 2002 - cell.com
Cholesteryl cyclodextrins, obtained by grafting a cholesterol moiety on the oligosaccharide
core, combine the size selectivity of the cyclodextrin cavity with the carrier properties of …

Ordering of Saturated and Unsaturated Lipid Membranes near Their Phase Transitions Induced by an Amphiphilic Cyclodextrin and Cholesterol

M Roux, V Bonnet, F Djedaïni-Pilard - Langmuir, 2019 - ACS Publications
When inserted in membranes of dimyristoyl phosphatidylcholine (DMPC), methylated β-
cyclodextrins with one (TrimβMLC) or two (TrimβDLC) lauryl acyl chains grafted onto the …

[PDF][PDF] Lipid lateral segregation driven by diacyl cyclodextrin interactions at the membrane surface

M Roux, S Moutard, B Perly, F Djedaini-Pilard - Biophysical journal, 2007 - cell.com
Cyclodextrins are hydrophilic molecular cages with a hydrophobic interior allowing the
inclusion of water-insoluble drugs. Amphiphilic cyclodextrins obtained by appending a …

Phase behavior of fully hydrated DMPC-amphiphilic cyclodextrin systems

S Lesieur, D Charon, P Lesieur… - Chemistry and physics …, 2000 - Elsevier
With the aim of exploring relationships between the chemical structure and the physico-
chemical properties of amphiphilic β-cyclodextrin, a reappraisal of the obtaining of pure …

Dynamic lipid lateral segregation driven by lauryl cyclodextrin interactions at the membrane surface

M Roux, E Sternin, V Bonnet, C Fajolles… - Langmuir, 2013 - ACS Publications
Amphiphilic cyclodextrins, with a cholesterol anchor (βChol) or an aspartic acid moiety
esterified by two lauryl acyl chains (βDLC), were designed to combine the inclusion ability of …

[PDF][PDF] Making Soft Magnetically-Orientable Membranes: An Alternative to Bicelles

AE Gravel, AA Arnold, DE Warschawski, I Marcotte - Biophysical Journal, 2018 - cell.com
Model lipid membranes have long been employed in a variety of biophysical techniques to
circumvent the complexity of natural membranes when studying their constituents or …

Cavity orientation regulated by mixture composition and clustering of amphiphilic cyclodextrins in phospholipid monolayers

JJ Pinzón Barrantes, B Maggio… - The Journal of …, 2017 - ACS Publications
Artificial supramolecular-hierarchical structures that emulate nature represent an
overcoming alternative for the design of new drug delivery systems. Thermodynamic and …

NMR of bicelles: orientation and mosaic spread of the liquid-crystal director under sample rotation

G Zandomeneghi, M Tomaselli, PTF Williamson… - Journal of biomolecular …, 2003 - Springer
Abstract Model-membrane systems composed of liquid-crystalline bicellar phases can be
uniaxially oriented with respect to a magnetic field, thereby facilitating structural and …

Change in morphology of dimyristoylphosphatidylcholine/bile salt derivative bicelle assemblies with dodecylmaltoside in the disk and ribbon phases

WC Leite, Y Wu, SV Pingali… - The Journal of …, 2022 - ACS Publications
Bicelles, composed of a mixture of long and short chain lipids, form nanostructured
molecular assemblies that are attractive lipid-membrane mimics for in vitro studies of integral …