Bovine lactoferrin inhibits dengue virus infectivity by interacting with heparan sulfate, low-density lipoprotein receptor, and DC-SIGN

JM Chen, YC Fan, JW Lin, YY Chen, WL Hsu… - International Journal of …, 2017 - mdpi.com
Bovine lactoferrin (bLF) presents in milk and has been shown to inhibit several viral
infections. Effective drugs are unavailable for the treatment of dengue virus (DENV) …

Role of sialylated glycans on bovine lactoferrin against influenza virus

X Wang, L Yue, L Dang, J Yang, Z Chen, X Wang… - Glycoconjugate …, 2021 - Springer
Influenza is a worldwide plague caused by the influenza virus (IAV) infection, which is
initiated by specific recognition with sialic acids on host cell surface. Bovine lactoferrin (bLf) …

Heparan sulfate-mediated binding of infectious dengue virus type 2 and yellow fever virus

R Germi, JM Crance, D Garin, J Guimet, H Lortat-Jacob… - Virology, 2002 - Elsevier
Dengue virus type 2 and Yellow fever virus are arthropod-borne flaviviruses causing
hemorrhagic fever in humans. Identification of virus receptors is important in understanding …

Bovine lactoferrin: involvement of metal saturation and carbohydrates in the inhibition of influenza virus infection

A Pietrantoni, MG Ammendolia… - Biochemistry and Cell …, 2012 - cdnsciencepub.com
Influenza is a highly contagious, acute respiratory illness, which represents one of the main
plagues worldwide. Even though some antiviral drugs are available, the alarming increase …

Lack of effect of bovine lactoferrin in respiratory syncytial virus replication and clinical disease severity in the mouse model

L Gualdi, S Mertz, AM Gomez, O Ramilo, A Wittke… - Antiviral research, 2013 - Elsevier
Background Lactoferrin (LF) is a glycoprotein present in human milk with known
antimicrobial effects. In vitro, LF has demonstrated antiviral activity against respiratory …

Dengue virus receptor

KIPJ Hidari, T Suzuki - Tropical medicine and health, 2011 - jstage.jst.go.jp
© 2011 Japanese Society of Tropical Medicine Abstract: Dengue virus is an arthropod-borne
virus transmitted by Aedes mosquitoes. Dengue virus causes fever and hemorrhagic …

Complement-mediated neutralization of dengue virus requires mannose-binding lectin

P Avirutnan, RE Hauhart, MA Marovich, P Garred… - MBio, 2011 - Am Soc Microbiol
Mannose-binding lectin (MBL) is a key soluble pathogen recognition protein of the innate
immune system that binds specific mannose-containing glycans on the surfaces of microbial …

Dengue and the lectin pathway of the complement system

R Kraivong, N Punyadee, MK Liszewski, JP Atkinson… - Viruses, 2021 - mdpi.com
Dengue is a mosquito-borne viral disease causing significant health and economic burdens
globally. The dengue virus (DENV) comprises four serotypes (DENV1-4). Usually, the …

Dengue virus infectivity depends on envelope protein binding to target cell heparan sulfate

Y Chen, T Maguire, RE Hileman, JR Fromm, JD Esko… - Nature medicine, 1997 - nature.com
Dengue virus is a human pathogen that has reemerged as an increasingly important public
health threat. We found that the cellular receptor utilized by dengue envelope protein to bind …

Inhibitory effect of bovine lactoferrin on human parainfluenza virus type 2 infection

H Yamamoto, Y Ura, M Tanemura, A Koyama… - Journal of Health …, 2010 - jstage.jst.go.jp
Human parainfluenza virus type 2 (hPIV-2) is one of the major human respiratory tract
pathogens of infants and children. hPIV-2 is a member of the genus Rubulavirus in the …