Alkaloids, the principal constituents in the caulis of Sinomenium acutum, have gained an
increasing interest over the past decades since they are widely employed as a clinical …

Sinomenium acutum stem is a popular traditional Chinese medicine used to treat bone and
joint diseases. Sinomenine is considered the only chemical marker for the quality control of …

Secondary metabolites accumulated in different tissues and cells of herbs are usually
bioactive components of herbal medicines. Thus, tissue-and cell-specific phytochemical …

Stephania epigaea Lo is an important herbal medicine used as antiphlogistic and analgesic
drugs. Its major components are dicentrine (1) and sinomenine (2). In the present study, a …

Sinomenium acutum stem is widely used to treat rheumatoid arthritis, gout, ankylosing
spondylitis and other diseases in China. However, its metabolism in vivo is still unclear. In …

The lateral root of Aconitum carmichaeli, a popular traditional Chinese medicine, has been
widely used to treat rheumatic diseases. For decades, diterpenoid alkaloids have dominated …

Danshen, the dried root of Salvia miltiorrhiza Bge., is a widely used commercially available
herbal drug, and unstable quality of different samples is a current issue. This study focused …

A statistic approach using response surface methodology (RSM) for optimization of the ultra-
high performance liquid chromatography (UHPLC) gradient and ionization response of …

The hyphenated technique of offline two-dimensional (2D) chromatography with high
resolution mass spectrometry (MS) was an efficient tool for separation and characterization …

Caulis Sinomenii is the dried plant stems of Sinomenium acutum and Sinomenium acutum
var. cinereum and has been used in Chinese medicine for treating rheumatic diseases for …