The potential role of miRNAs in the pathogenesis of cardiovascular diseases–A focus on signaling pathways interplay

EG Khidr, AI Abulsoud, AA Doghish… - … -Research and Practice, 2023 - Elsevier
For the past two decades since their discovery, scientists have linked microRNAs (miRNAs)
to posttranscriptional regulation of gene expression in critical cardiac physiological and …

[HTML][HTML] Overview of microRNAs in cardiac hypertrophy, fibrosis, and apoptosis

J Wang, OW Liew, AM Richards, YT Chen - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are non-coding RNAs that play essential roles in modulating the gene
expression in almost all biological events. In the past decade, the involvement of miRNAs in …

miRNAs orchestration of cardiovascular diseases–Particular emphasis on diagnosis, and progression

EGE Elsakka, AI Abulsoud, HA El-Mahdy… - … -Research and Practice, 2023 - Elsevier
MicroRNAs (miRNAs; miRs) are small non-coding ribonucleic acids sequences vital in
regulating gene expression. They are significant in many biological and pathological …

[HTML][HTML] miRNAs at the heart of the matter

Z Wang, X Luo, Y Lu, B Yang - Journal of Molecular Medicine, 2008 - Springer
Cardiovascular disease is among the main causes of morbidity and mortality in developed
countries. The pathological process of the heart is associated with altered expression profile …

[HTML][HTML] The role of microRNAs in myocardial infarction: from molecular mechanism to clinical application

T Sun, YH Dong, W Du, CY Shi, K Wang… - International journal of …, 2017 - mdpi.com
MicroRNAs (miRNAs) are a class of small single-stranded and highly conserved non-coding
RNAs, which are closely linked to cardiac disorders such as myocardial infarction (MI) …

[HTML][HTML] miRNA dysregulation in cardiovascular diseases: current opinion and future perspectives

F Sessa, M Salerno, M Esposito, G Cocimano… - International Journal of …, 2023 - mdpi.com
MicroRNAs (miRNAs), small noncoding RNAs, are post-transcriptional gene regulators that
can promote the degradation or decay of coding mRNAs, regulating protein synthesis. Many …

MicroRNAs: role in cardiovascular biology and disease

C Zhang - Clinical science, 2008 - portlandpress.com
miRNAs (microRNAs) comprise a novel class of endogenous, small, non-coding RNAs that
negatively regulate gene expression via degradation or translational inhibition of their target …

The role of microRNA in modulating myocardial ischemia-reperfusion injury

Y Ye, JR Perez-Polo, J Qian… - Physiological …, 2011 - journals.physiology.org
MicroRNAs (miRNAs) are small (∼ 22 nt) noncoding single-stranded RNA molecules that
downregulate gene expression. Studies have shown that miRNAs control diverse aspects of …

MicroRNAs and ischemic heart disease: towards a better comprehension of pathogenesis, new diagnostic tools and new therapeutic targets

P Silvestri, C Di Russo, S Rigattieri… - Recent Patents on …, 2009 - ingentaconnect.com
MicroRNAs are key, recently discovered, regulators of gene expression. They are involved
in many physiological cellular pathways so it is not surprising that an altered microRNA …

MicroRNAs and cardiovascular diseases

K Ono - MicroRNAs in Medicine, 2013 - Wiley Online Library
Recent gain‐and loss‐of‐function studies using in vitro and in vivo models have revealed
distinct roles for specific miRNAs in cardiovascular development, physiological functions …