Transition metal complexes and photodynamic therapy from a tumor-centered approach: challenges, opportunities, and highlights from the development of TLD1433
Transition metal complexes are of increasing interest as photosensitizers in photodynamic
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …
therapy (PDT) and, more recently, for photochemotherapy (PCT). In recent years, Ru (II) …
Ru (II) containing photosensitizers for photodynamic therapy: A critique on reporting and an attempt to compare efficacy
MA Munegowda, A Manalac, M Weersink… - Coordination chemistry …, 2022 - Elsevier
Ruthenium (II)-based coordination complexes have emerged as photosensitizers (PSs) for
photodynamic therapy (PDT) in oncology as well as antimicrobial indications and have great …
photodynamic therapy (PDT) in oncology as well as antimicrobial indications and have great …
Combination of light and Ru (II) polypyridyl complexes: Recent advances in the development of new anticancer drugs
L Conti, E Macedi, C Giorgi, B Valtancoli… - Coordination Chemistry …, 2022 - Elsevier
The increasing impact of cancer on worldwide mortality makes the research of novel
chemotherapeutic agents a current and challenging issue. In the recent years, transition …
chemotherapeutic agents a current and challenging issue. In the recent years, transition …
Transition metal complexes as photosensitizers for integrated cancer theranostic applications
J Li, T Chen - Coordination Chemistry Reviews, 2020 - Elsevier
Light, oxygen and photosensitizers (PSs) are the three separate elements that have been
applied in combination in the phototherapy of cancers in the past decades. Currently …
applied in combination in the phototherapy of cancers in the past decades. Currently …
Rationally designed long-wavelength absorbing Ru (II) polypyridyl complexes as photosensitizers for photodynamic therapy
J Karges, F Heinemann, M Jakubaszek… - Journal of the …, 2020 - ACS Publications
The utilization of photodynamic therapy (PDT) for the treatment of various types of cancer
has gained increasing attention over the last decades. Despite the clinical success of …
has gained increasing attention over the last decades. Despite the clinical success of …
Transition metal complexes as photosensitisers in one-and two-photon photodynamic therapy
Photodynamic therapy (PDT) exploits light-activated compounds for therapeutic use. It relies
on a photosensitiser (PS) that is inactive in the absence of light. When irradiated, the PS …
on a photosensitiser (PS) that is inactive in the absence of light. When irradiated, the PS …
Harnessing ruthenium (II) as photodynamic agents: Encouraging advances in cancer therapy
Despite their past triumphs, platinum-based therapeutics remain limited by chemo-
resistance and severe side effects. As an alternative therapeutic modality which bypasses …
resistance and severe side effects. As an alternative therapeutic modality which bypasses …
Recent advances in noble metal complex based photodynamic therapy
Photodynamic therapy (PDT) utilizes light-activated photosensitizers (PSs) to generate toxic
species for therapeutics. It has become an emerging solution for cancer treatment because …
species for therapeutics. It has become an emerging solution for cancer treatment because …
Control and utilization of ruthenium and rhodium metal complex excited states for photoactivated cancer therapy
The use of visible light to produce highly selective and potent drugs through photodynamic
therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed …
therapy (PDT) holds much potential in the treatment of cancer. PDT agents can be designed …
Near-infrared absorbing Ru (II) complexes act as immunoprotective photodynamic therapy (PDT) agents against aggressive melanoma
Mounting evidence over the past 20 years suggests that photodynamic therapy (PDT), an
anticancer modality known mostly as a local treatment, has the capacity to invoke a systemic …
anticancer modality known mostly as a local treatment, has the capacity to invoke a systemic …