Retinal toxicity induced by chemical agents

D Souza Monteiro de Araújo, R Brito… - International Journal of …, 2022 - mdpi.com
Vision is an important sense for humans, and visual impairment/blindness has a huge
impact in daily life. The retina is a nervous tissue that is essential for visual processing since …

Retinal and ocular toxicity in ocular application of drugs and chemicals–part II: retinal toxicity of current and new drugs

FM Penha, EB Rodrigues, M Maia, BA Furlani… - Ophthalmic …, 2010 - karger.com
Aims: Retinal pharmacotherapy has gained great importance for the treatment of various
retinal diseases. An increasing number of drugs have been constantly released into the …

Retinal toxicity of systemic medications

LT Labriola, D Jeng, AA Fawzi - International ophthalmology …, 2012 - journals.lww.com
Similar to the brain with its blood-brain barrier, the retina is somewhat protected from
systemic chemicals by virtue of the inner and outer blood-retina barrier formed by the tight …

Phototoxicity to the retina: mechanisms of damage

RD Glickman - International journal of toxicology, 2002 - journals.sagepub.com
Light damage to the retina occurs through three general mechanisms involving thermal,
mechanical, or photochemical effects. The particular mechanism activated depends on the …

Role of free radicals in ocular diseases: An overview

PK Suresh, AK Sah, SJ Daharwal - Research Journal of …, 2014 - indianjournals.com
The aim of the present review is to focus on the potential consequences of free radicals in
human health and disease with special reference to ocular disorders. The balance between …

Drug induced retinopathy

W Meier-Ruge, AM Potts - CRC Critical Reviews in Toxicology, 1972 - Taylor & Francis
Druginduced retinal lesions are not acquisitions of modern drug therapy. Eyesight lesions
have been known as dreaded side-effects of treatment since the earliest beginnings of …

Three major causes of metabolic retinal degenerations and three ways to avoid them

A Kovács-Valasek, T Rák, E Pöstyéni, A Csutak… - International journal of …, 2023 - mdpi.com
An imbalance of homeostasis in the retina leads to neuron loss and this eventually results in
a deterioration of vision. If the stress threshold is exceeded, different protective/survival …

Retinal and ocular toxicity in ocular application of drugs and chemicals–part I: animal models and toxicity assays

FM Penha, EB Rodrigues, M Maia, E Dib… - Ophthalmic …, 2010 - karger.com
Aims: Experimental retinal research has gained great importance due to the ophthalmic
pharmacotherapy era. An increasing number of drugs are constantly released into the …

Visual system: An understudied target of aquatic toxicology

L Chen - Aquatic Toxicology, 2020 - Elsevier
Visual system is increasingly recognized as a sensitive target of xenobiotics in aquatic
ecosystems. Various environmental pollutants of distinct physicochemical properties are …

Oxidative stress, ocular disease and diabetes retinopathy

O Tangvarasittichai… - Current pharmaceutical …, 2018 - ingentaconnect.com
Background: Oxidative stress is caused by free radicals or oxidant productions, including
lipid peroxidation, protein modification, DNA damage and apoptosis or cell death and results …